A multifunctional carbon dots with near-infrared fluorescence for Au3+/ Hg2+ and GSH detection and tumor diagnosis

被引：17
|
作者：
Yang, Xiaojing [1 ]
Wang, Yingying [1 ]
Xu, Jingjing [1 ]
Zhao, Mei-Xia [1 ]
机构：
[1] Henan Univ, Key Lab Nat Med & Immune Engn Henan Prov, Kaifeng 475004, Peoples R China
来源：
MICROCHEMICAL JOURNAL | 2021年 / 165卷
基金：
中国国家自然科学基金;
关键词：
Carbon dots; Near-infrared; Fluorescence; Noble metal ions; Probe; Tumor; LABEL-FREE DETECTION; RED EMISSION; ONE-POT; PROBE; GREEN; GLUTATHIONE; NITROGEN; SULFIDE; CELLS; STATE;
D O I：
10.1016/j.microc.2021.106033
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
In recent years, carbon dots (CDs) have shown potential applications in fluorescence tracing and imaging due to their excellent optical and chemical properties. In this work, a new type of carbon dots (Cy7-CDs) with nearinfrared absorption and emission was synthesized from cyanine dyes and polyethylene glycol by hydrothermal reaction. The prepared Cy7-CDs exhibited low toxicity and excellent biocompatibility, which were applied to detect the noble metal ions Au3+/Hg2+ and glutathione via the ?on?off-on? mode. In addition, in vivo fluorescence images demonstrated that Cy7-CDs could efficiently accumulate in the tumor. Therefore, Cy7-CDs could act as a multi-functional probe for biological sensing and tumor diagnosis.
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页数：6
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