Ciliary Doublet Microtubules at Near-Atomic Resolution

被引:1
|
作者
Pazour, Gregory J. [1 ]
King, Stephen M. [2 ]
机构
[1] Univ Massachusetts, Med Sch, Program Mol Med, Biotech 2, Suite 213,373 Plantation St, Worcester, MA 01605 USA
[2] Univ Connecticut, Hlth Ctr, Dept Mol Biol & Biophys, 263 Farmington Ave, Farmington, CT 06030 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/j.cell.2019.10.013
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The beauty of the eukaryotic cilium has been appreciated since electron microscopy first revealed its 9-fold symmetry. In this issue of Cell, Ma et al. use cryoelectron microscopy and modeling to define doublet microtubules at near-atomic resolution, revealing an intricate array of proteins decorating the inner and outer surfaces.
引用
收藏
页码:805 / 807
页数:4
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