Advances in Management of Acute Pancreatitis

被引:60
作者
Janisch, Nigeen H. [1 ]
Gardner, Timothy B. [1 ,2 ]
机构
[1] Geisel Sch Med Dartmouth, Hanover, NH USA
[2] Dartmouth Hitchcock Med Ctr, Sect Gastroenterol & Hepatol, 1 Med Ctr Dr, Lebanon, NH 03756 USA
关键词
Acute pancreatitis; Medical management; Fluid resuscitation; Antibiotics; Walled-off pancreatic necrosis; Bedside Index for Severity in Acute Pancreatitis; Prognostication; ACUTE NECROTIZING PANCREATITIS; EARLY FLUID RESUSCITATION; CLINICAL-TRIAL; METAANALYSIS; MORTALITY; NECROSIS; HEMOCONCENTRATION; MICROCIRCULATION; OCTREOTIDE; GUIDELINES;
D O I
10.1016/j.gtc.2015.10.004
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
This article reviews advances in the management of acute pancreatitis. Medical treatment has been primarily supportive for this diagnosis, and, despite extensive research efforts, there are no pharmacologic therapies that improve prognosis. The current mainstay of management, notwithstanding the ongoing debate regarding the volume, fluid type, and rate of administration, is aggressive intravenous fluid resuscitation. Although antibiotics were used consistently for prophylaxis in severe acute pancreatitis to prevent infection, they are no longer used unless infection is documented. Enteral nutrition, especially in patients with severe acute pancreatitis, is considered a cornerstone in management of this disease.
引用
收藏
页码:1 / +
页数:9
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