Synthetic Micro/nanoengineered Tools to Study Mechanobiology and Its Regulatory Role for Human Pluripotent Stem Cells

被引:0
作者
Fu, Jianping [1 ]
Sun, Yubing [1 ]
Yong, Koh Meng Aw [1 ]
机构
[1] Univ Michigan, Dept Mech Engn, Ann Arbor, MI 48109 USA
来源
2013 13TH IEEE CONFERENCE ON NANOTECHNOLOGY (IEEE-NANO) | 2013年
关键词
RIGIDITY; STRETCH; FORCES;
D O I
暂无
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
In this talk, I will discuss our recent effort using synthetic micro/nanoengineered tools to study mechano-sensitive and -responsive behaviors of human pluripotent stem cells (hPSCs) and the underlying molecular and cellular mechanisms.
引用
收藏
页码:11 / 14
页数:4
相关论文
共 14 条
  • [1] Mechanical regulation of cell function with geometrically modulated elastomeric substrates
    Fu, Jianping
    Wang, Yang-Kao
    Yang, Michael T.
    Desai, Ravi A.
    Yu, Xiang
    Liu, Zhijun
    Chen, Christopher S.
    [J]. NATURE METHODS, 2010, 7 (09) : 733 - U95
  • [2] Mapping cell-matrix stresses during stretch reveals inelastic reorganization of the cytoskeleton
    Gavara, Nuria
    Roca-Cusachs, Pere
    Sunyer, Raimon
    Farre, Ramon
    Navajas, Daniel
    [J]. BIOPHYSICAL JOURNAL, 2008, 95 (01) : 464 - 471
  • [3] Mechanical Properties of Cellularly Responsive Hydrogels and Their Experimental Determination
    Kloxin, April M.
    Kloxin, Christopher J.
    Bowman, Christopher N.
    Anseth, Kristi S.
    [J]. ADVANCED MATERIALS, 2010, 22 (31) : 3484 - 3494
  • [4] Mechanical tugging force regulates the size of cell-cell junctions
    Liu, Zhijun
    Tan, John L.
    Cohen, Daniel M.
    Yang, Michael T.
    Sniadecki, Nathan J.
    Ruiz, Sami Alom
    Nelson, Celeste M.
    Chen, Christopher S.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (22) : 9944 - 9949
  • [5] A silicone-based stretchable micropost array membrane for monitoring live-cell subcellular cytoskeletal response
    Mann, Jennifer M.
    Lam, Raymond H. W.
    Weng, Shinuo
    Sun, Yubing
    Fu, Jianping
    [J]. LAB ON A CHIP, 2012, 12 (04) : 731 - 740
  • [6] Is the mechanical activity of epithelial cells controlled by deformations or forces?
    Saez, A
    Buguin, A
    Silberzan, P
    Ladoux, B
    [J]. BIOPHYSICAL JOURNAL, 2005, 89 (06) : L52 - L54
  • [7] Magnetic microposts as an approach to apply forces to living cells
    Sniadecki, Nathan J.
    Anguelouch, Alexandre
    Yang, Michael T.
    Lamb, Corinne M.
    Liu, Zhijun
    Kirschner, Stuart B.
    Liu, Yaohua
    Reich, Daniel H.
    Chen, Christopher S.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (37) : 14553 - 14558
  • [8] Mechanobiology: a new frontier for human pluripotent stem cells
    Sun, Yubing
    Fu, Jianping
    [J]. INTEGRATIVE BIOLOGY, 2013, 5 (03) : 450 - 457
  • [9] Mechanics Regulates Fate Decisions of Human Embryonic Stem Cells
    Sun, Yubing
    Villa-Diaz, Luis G.
    Lam, Raymond H. W.
    Chen, Weiqiang
    Krebsbach, Paul H.
    Fu, Jianping
    [J]. PLOS ONE, 2012, 7 (05):
  • [10] Forcing Stem Cells to Behave: A Biophysical Perspective of the Cellular Microenvironment
    Sun, Yubing
    Chen, Christopher S.
    Fu, Jianping
    [J]. ANNUAL REVIEW OF BIOPHYSICS, VOL 41, 2012, 41 : 519 - 542