Age-related changes in the cerebrospinal fluid level of β-endorphin and substance P -: Short communication

被引：6

作者：

Nagamitsu, S

Matsuishi, T

Komori, H

Yamashita, Y

Eguchi, H

Ichikawa, K

Fujimoto, T

Kato, H

机构：

[1] Kurume Univ, Sch Med, Dept Pediat & Child Hlth, Kurume, Fukuoka 830, Japan

[2] Kitakyushu City Yahata Hosp, Ctr Emergency Med, Dept Pediat, Kitakyushu, Fukuoka, Japan

[3] Fujimoto Childrens Hosp, Ohita, Japan

来源：

JOURNAL OF NEURAL TRANSMISSION | 1998年 / 105卷 / 01期

关键词：

cerebrospinal fluid; beta-endorphin; substance P; age;

D O I：

10.1007/s007020050037

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To evaluate the early age-related changes in neuropeptides, we have measured the cerebrospinal fluid (CSF) levels of beta-endorphin and substance P in young patients over a range of ages. Specimens of CSF were obtained from 39 neurologically normal children, aged 1 month to 10 years of age, and in 9 adult controls. CSF levels of both neuropeptides were observed to peak during the first year of life, and showed a negative correlation with increasing age. A significant positive correlation was observed between the CSF level of beta-endorphin and that of substance P.

引用

页码：53 / 58

页数：6

共 20 条

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BACH FW, 1992, CLIN CHEM, V38, P847

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