SOME PLANT EXTRACTS USED IN PHARMACOLOGICALLY ACTIVITY OF ANXIOLYTICS, ANTIDEPRESSANT, ANALGESIC, AND ANTI-INFLAMMATORY ACTIVITY

The aim of present study was to assess the anti-inflammatory activity of polyherbal formulation of leaves of Azadiracta indica and rhizome of Curcuma longa. The mature green leaves of Azadiracta indica and Curcuma longa were collected and authenticated. Extractions of dried leaves and rhizome were carried out with ethanol in soxhlet apparatus. The polyherbal formulation showed the significant anti-inflammatory activity comparable to the standard drug Indomethacin against carrageenan induced rat paw edema method. The polyherbal formulation reduced the inflammation induced by carrageenan by 43.3% and 57.73% on oral administration at 100 mg/kg and 200 mg/kg respectively as compared to the control treated group an analgesic activity comparable to the standard drug tramadol HCl. Antidepressant activity and Anxiolytics comparable to the standard drug Fluoxetine HCl.