Children diagnosed with attention deficit disorder and their hospitalisations: population data linkage study

被引:26
作者
Silva, Desiree [1 ,2 ,3 ]
Colvin, Lyn [1 ]
Hagemann, Erika [4 ]
Stanley, Fiona [1 ,2 ]
Bower, Carol [1 ,2 ]
机构
[1] Univ Western Australia, Telethon Kids Inst, Perth 6872, Australia
[2] Univ Western Australia, Sch Paediat & Child Hlth, Perth, WA 6009, Australia
[3] Univ Western Australia, Perth, WA 6009, Australia
[4] Fremantle Speech Pathol Serv, Fremantle, WA, Australia
基金
澳大利亚研究理事会;
关键词
ADHD; Postnatal risk factors; Otitis media; Sleep apnoea; Injury; Poisons; Hospitalisation; OBSTRUCTIVE SLEEP-APNEA; DEFICIT/HYPERACTIVITY DISORDER; RISK-FACTORS; ADHD; BIRTH; ABNORMALITIES; INFLAMMATION; COMORBIDITY; INFECTIONS; PREVALENCE;
D O I
10.1007/s00787-014-0545-8
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
Examine the hospital admission risk in young children who are subsequently diagnosed with attention deficit hyperactivity disorder (ADHD). We conducted a population-based, record linkage study. Records of all non-Aboriginal children under 18 years who met the DSMIV/ICD10 criteria for ADHD and prescribed stimulant medication in Western Australia between 2003 and 2007 (n = 11,902) were linked to two other health data systems-the hospital morbidity data system and the midwives notification system (MNS). The non-ADHD reference population (n = 27,304) was randomly selected from the MNS. Compared with controls, children under 4 years who subsequently were diagnosed and treated for ADHD were 70 % [odds ratio (OR) 1.70; 95 % confidence intervals (CI) 1.62-1.77] more likely to be admitted to hospital under 4 years of age. There was an increased risk for injury or poison (OR 1.73; 95 % CI 1.59-1.88), respiratory disease (OR 1.49; 95 % CI 1.40-1.59), ear disease (OR 2.03; 95 % CI 1.86-2.21), infectious diseases (OR 1.68; 95 % CI 1.53-1.85) and neurological conditions (OR 2.03; 95 % CI 1.68-2.44). Admissions under 4 years of age for head injuries, burns, poisons, all other injuries, diseases of the tonsils and adenoids, asthma and early infections were all more common amongst children subsequently diagnosed with and treated for ADHD. There is significant early hospital morbidity for children subsequently diagnosed with ADHD. Multiple aetiologies and causal pathways need to be considered where some of these may include early infections, inflammatory conditions, epilepsy and injuries. Future studies should look at which of these conditions may be on the causal pathway or likely early markers for ADHD.
引用
收藏
页码:1043 / 1050
页数:8
相关论文
共 52 条
[11]   Childhood behavior disorders and injuries among children and youth: A population-based study [J].
Brehaut, JC ;
Miller, A ;
Raina, P ;
McGrail, KM .
PEDIATRICS, 2003, 111 (02) :262-269
[12]   Postnatal infection is associated with widespread abnormalities of brain development in premature newborns [J].
Chau, Vann ;
Brant, Rollin ;
Poskitt, Kenneth J. ;
Tam, Emily W. Y. ;
Synnes, Anne ;
Miller, Steven P. .
PEDIATRIC RESEARCH, 2012, 71 (03) :274-279
[13]   Environmental risk factors for attention-deficit hyperactivity disorder [J].
Das Banerjee, Tania ;
Middleton, Frank ;
Faraone, Stephen V. .
ACTA PAEDIATRICA, 2007, 96 (09) :1269-1274
[14]   Epilepsy in Children With Attention-Deficit/Hyperactivity Disorder [J].
Davis, Shanlee M. ;
Katusic, Slavica K. ;
Barbaresi, William J. ;
Killian, Jill ;
Weaver, Amy L. ;
Ottman, Ruth ;
Wirrell, Elaine C. .
PEDIATRIC NEUROLOGY, 2010, 42 (05) :325-330
[15]  
Department of Health, 2012, W AUSTR STIM REG SCH
[16]   Comorbidity of Asthma With ADHD [J].
Fasmer, Ole Bernt ;
Riise, Trond ;
Eagan, Tomas Mikal ;
Lund, Anders ;
Dilsaver, Steven C. ;
Hundal, Oivind ;
Oedegaard, Ketil J. .
JOURNAL OF ATTENTION DISORDERS, 2011, 15 (07) :564-571
[17]   In Utero Exposure to Ischemic-Hypoxic Conditions and Attention-Deficit/Hyperactivity Disorder [J].
Getahun, Darios ;
Rhoads, George G. ;
Demissie, Kitaw ;
Lu, Shou-En ;
Quinn, Virginia P. ;
Fassett, Michael J. ;
Wing, Deborah A. ;
Jacobsen, Steven J. .
PEDIATRICS, 2013, 131 (01) :E53-E61
[18]   Sleep-disordered breathing and neurobehavioral outcomes - In search of clear markers for children at risk - Abstract and commentary [J].
Giordani, Bruno ;
Chervin, Ronald D. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2008, 299 (17) :2078-2080
[19]   Role of Perinatal Inflammation in Cerebral Palsy [J].
Girard, Sylvie ;
Kadhim, Hazim ;
Roy, Melanie ;
Lavoie, Karine ;
Brochu, Marie-Elsa ;
Larouche, Annie ;
Sebire, Guillaume .
PEDIATRIC NEUROLOGY, 2009, 40 (03) :168-174
[20]   Sleep Study Abnormalities in Children With Attention Deficit Hyperactivity Disorder [J].
Goraya, Jatinder S. ;
Cruz, Marcos ;
Valencia, Ignacio ;
Kaleyias, Joseph ;
Khurana, Divya S. ;
Hardison, Huntley H. ;
Marks, Harold ;
Legido, Agustin ;
Kothare, Sanjeev V. .
PEDIATRIC NEUROLOGY, 2009, 40 (01) :42-46