The compositional difference between ankle and knee cartilage demonstrated by T2 mapping at 7 Tesla MR

被引:28
作者
Juras, Vladimir [1 ,2 ]
Zbyn, Stefan [1 ]
Mlynarik, Vladimir [1 ]
Szomolanyi, Pavol [1 ,2 ]
Hager, Benedikt [1 ]
Baer, Peter [1 ]
Frollo, Ivan [2 ]
Tratting, Siegfried [1 ,3 ,4 ]
机构
[1] Med Univ Vienna, High Field MR Ctr, Dept Biomed Imaging & Image Guided Therapy, Vienna, Austria
[2] Slovak Acad Sci, Dept Imaging Methods, Inst Measurement Sci, Bratislava, Slovakia
[3] Christian Doppler Lab Clin Mol MR Imaging, Vienna, Austria
[4] Ludwig Boltzmann Inst Expt & Clin Traumatol, Austrian Cluster Tissue Regenerat, Vienna, Austria
基金
奥地利科学基金会;
关键词
T2; mapping; Cartilage; 3D-TESS; Ankle; knee; ARTICULAR-CARTILAGE; RELAXATION-TIME; OSTEOARTHRITIS; JOINTS; RECONSTRUCTION; RELAXOMETRY; THICKNESS; GENDER;
D O I
10.1016/j.ejrad.2016.01.021
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Objectives: The aim was to systematically compare T2 relaxation times of the knee and ankle cartilage within subjects at 7T. Methods: Ten healthy volunteers were examined by 7 Tesla MR using a three-dimensional triple-echo steady state sequence (3D-TESS). The differences between seven cartilage compartments (patella, femur, proximal tibia, and distal tibia and talus in both medial and lateral facet) were analyzed by ANOVA. Results: The results showed statistically significantly higher T2 (mean +/- standard deviation, in milliseconds) values in patellar (25.8 +/- 1.2) and femoral (24.9 +/- 1.3) cartilage compared to the tibial (19.2 +/- 1) and talar (18.1 +/- 0.6 ms) cartilage. The cartilages of the medial and lateral facet in the ankle joint were not significantly different (p > 0.05). Conclusions: This is the first study to systematically compare within-subject T2 values in the knee and ankle non-invasively, in vivo. Our results are in agreement with the previous findings demonstrating different biochemical and biomechanical properties between the knee and ankle cartilage. (c) 2016 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:771 / 777
页数:7
相关论文
共 35 条
[1]   Quantitative T2 mapping of the patella at 3.0 T is sensitive to early cartilage degeneration, but also to loading of the knee [J].
Apprich, S. ;
Mamisch, T. C. ;
Welsch, G. H. ;
Stelzeneder, D. ;
Albers, C. ;
Totzke, U. ;
Trattnig, S. .
EUROPEAN JOURNAL OF RADIOLOGY, 2012, 81 (04) :E438-E443
[2]   BIOMECHANICAL TOPOGRAPHY OF HUMAN ANKLE CARTILAGE [J].
ATHANASIOU, KA ;
NIEDERAUER, GG ;
SCHENCK, RC .
ANNALS OF BIOMEDICAL ENGINEERING, 1995, 23 (05) :697-704
[3]   Rapid and Accurate T2 Mapping from Multi-Spin-Echo Data Using Bloch-Simulation-Based Reconstruction [J].
Ben-Eliezer, Noam ;
Sodickson, Daniel K. ;
Block, Kai Tobias .
MAGNETIC RESONANCE IN MEDICINE, 2015, 73 (02) :809-817
[4]   T2* Mapping of Acetabular and Femoral Hip Joint Cartilage at 3 T A Prospective Controlled Study [J].
Bittersohl, Bernd ;
Miese, Falk R. ;
Hosalkar, Harish S. ;
Mamisch, Tallal C. ;
Antoch, Gerald ;
Krauspe, Ruediger ;
Zilkens, Christoph .
INVESTIGATIVE RADIOLOGY, 2012, 47 (07) :392-397
[5]   Sensitivity of MRI to proteoglycan depletion in cartilage: comparison of sodium and proton MRI [J].
Borthakur, A ;
Shapiro, EM ;
Beers, J ;
Kudchodkar, S ;
Kneeland, JB ;
Reddy, R .
OSTEOARTHRITIS AND CARTILAGE, 2000, 8 (04) :288-293
[6]   MRI techniques in early stages of cartilage disease [J].
Burstein, D ;
Bashir, A ;
Gray, ML .
INVESTIGATIVE RADIOLOGY, 2000, 35 (10) :622-638
[7]  
Burstein D, 2001, MAGNET RESON MED, V45, P36, DOI 10.1002/1522-2594(200101)45:1<36::AID-MRM1006>3.0.CO
[8]  
2-W
[9]  
Chubinskaya S, 1996, LAB INVEST, V74, P232
[10]   Gender differences in knee cartilage volume as measured by magnetic resonance imaging [J].
Cicuttini, FM ;
Forbes, A ;
Morris, K ;
Darling, S ;
Bailey, M ;
Stuckey, S .
OSTEOARTHRITIS AND CARTILAGE, 1999, 7 (03) :265-271