Magnetically separable Fe3O4 nanoparticles: an efficient catalyst for the synthesis of propargylamines

被引：138

作者：

Sreedhar, B. ^{[1
]}

Kumar, A. Suresh ^{[1
]}

Reddy, P. Surendra ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Council Sci & Ind Res, Inorgan & Phys Chem Div, Hyderabad 500607, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 14期

关键词：

Propargylamines; Magnetically separable Fe3O4 nanoparticles; Terminal alkynes; Amines; Aldehydes; 3-COMPONENT COUPLING REACTION; TERMINAL ALKYNES; DIRECT-ADDITION; ALDEHYDE; COPPER; AMINE; COMPLEX; SILVER; HYDROGENATION; CONDENSATION;

D O I：

10.1016/j.tetlet.2010.02.016

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Magnetically separable Fe3O4 nanoparticles endow with all efficient and economic route for the synthesis of propargylamines by the three-component Coupling of aldehyde, amine, and alkyne through C-H activation. The reaction is especially effective for reactions involving aliphatic aldehydes and no additional co-catalyst or activator is required. High catalytic activity and ease of recovery using all external magnetic field are additional eco-friendly attributes of this catalytic system. The catalyst was recycled for five times without a significant loss of catalytic activity. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：1891 / 1895

页数：5

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