Initiation of angiogenic Kaposi's sarcoma lesions

被引:65
作者
Hayward, GS [1 ]
机构
[1] Johns Hopkins Univ, Sch Med, Sydney Kimmel Oncol Ctr, Viral Oncol Program, Baltimore, MD 21231 USA
关键词
D O I
10.1016/S1535-6108(03)00002-3
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Anew mouse model reported in this issue of Cancer Cell implies that VEGF/KDR-mediated paracrine effects induced by the lytic cycle vGPCR signaling protein encoded by human Kaposi's sarcoma-associated herpesvirus (KSHV or HHV8) may be involved in promoting the proliferation of the KSHV latently infected spindle endothelial cells of Kaposi's sarcoma.
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页码:1 / 3
页数:3
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