Magnetic nanoparticles in developing electrochemical sensors for pharmaceutical and biomedical applications

被引:97
作者
Mollarasouli, Fariba [1 ]
Zor, Erhan [2 ,3 ]
Ozcelikay, Goksu [4 ]
Ozkan, Sibel A. [4 ]
机构
[1] Univ Yasuj, Dept Chem, Yasuj 7591874831, Iran
[2] Necmettin Erbakan Univ, AK Educ Fac, Dept Sci Educ, TR-42090 Konya, Turkey
[3] Necmettin Erbakan Univ, Sci & Technol Res & Applicat Ctr BITAM, Biomat & Biotechnol Lab, TR-42090 Konya, Turkey
[4] Ankara Univ, Fac Pharm, Dept Analyt Chem, TR-06560 Ankara, Turkey
关键词
Magnetic nanoparticles; Electrochemical sensor; Pharmaceutical; Biomedical; Biomarkers diagnosis; VOLTAMMETRIC DETERMINATION; GOLD NANOPARTICLES; MODIFIED ELECTRODE; NANOMATERIALS; ACID; NANOCOMPOSITE; BIOSENSORS; MICELLES; SERUM; IRON;
D O I
10.1016/j.talanta.2021.122108
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A revolutionary impact on the pharmaceutical and biomedical applications has been arisen in the few years to come as a result of the advances made in magnetic nanoparticles (MNPs) research. The use of MNPs opens wide opportunities in diagnostics, drug and gene delivery, in vivo imaging, magnetic separation, and hyperthermia therapy, etc. Besides, their possible integration in sensors makes them an ideal essential element of innovative pharmaceutical and biomedical applications. Nowadays, MNPs-based electrochemical sensors have attracted great attention to pharmaceutical and biomedical applications owing to their high sensitivity, stability. Selectivity towards the target as well as their simplicity of manufacture. Therefore, this review focus on recent advances with cutting-edge approaches dealing with the synthesis, design, and advantageous analytical performance of MNPs in the electrochemical sensors utilized for pharmaceutical and biomedical applications between 2015 and 2020. The challenges existing in this research area and some potential strategies/future perspectives for the rational design of electrochemical sensors are also outlined.
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页数:23
相关论文
共 154 条
[1]  
ABDELSHAFI NA, 2019, BIOSENS BIOELECTRON, V11, P492
[2]   Sensitive determination of the anti-viral drug valganciclovir by a nafion/magnetic nanoparticle-graphene/GCE as a voltammetric sensor [J].
Ahmadi, Elahe ;
Gholivand, Mohammad Bagher .
ANALYTICAL METHODS, 2019, 11 (36) :4659-4667
[3]   Fabrication of hydrazine sensor based on silica-coated Fe2O3 magnetic nanoparticles prepared by a rapid microwave irradiation method [J].
Akhter, Hashi ;
Murshed, Jannatul ;
Rashed, Md. A. ;
Oshima, Yoshifumi ;
Nagao, Yuki ;
Rahman, Mohammed M. ;
Asiri, Abdullah M. ;
Hasnat, M. A. ;
Uddin, Md. Nizam ;
Siddiquey, Iqbal Ahmed .
JOURNAL OF ALLOYS AND COMPOUNDS, 2017, 698 :921-929
[4]  
Alonso J, 2018, MICRO NANO TECHNOL, P1, DOI 10.1016/B978-0-12-813904-2.00001-2
[5]   Electrochemical tropomyosin allergen immunosensor for complex food matrix analysis [J].
Angulo-Ibanez, A. ;
Eletxigerra, U. ;
Lasheras, X. ;
Campuzano, S. ;
Merino, S. .
ANALYTICA CHIMICA ACTA, 2019, 1079 :94-102
[6]  
[Anonymous], 2014, CLIN APPL BODY SENSO
[7]  
ARAGAY G, 2012, SUSTAINABILITY-BASEL, V84, P49
[8]  
ARVAND M, 2017, RSC ADV, V238, P346
[9]   Novel electrochemical biosensor based on PVP capped CoFe2O4@CdSe core-shell nanoparticles modified electrode for ultra-trace level determination of rifampicin by square wave adsorptive stripping voltammetry [J].
Asadpour-Zeynali, Karim ;
Mollarasouli, Fariba .
BIOSENSORS & BIOELECTRONICS, 2017, 92 :509-516
[10]  
ASGARI S, 2019, J PHYS CHEM-US, V86, P118