Hematological abnormalities in patients with dengue

被引：21

作者：

Luna de Oliveira, Eveny Cristine ^{[1
]}

Jardim Cury Pontes, Elenir Rose ^{[2
]}

da Cunha, Rivaldo Venancio ^{[3
]}

Froes, Iris Bucker ^{[1
]}

do Nascimento, Delso ^{[1
]}

机构：

[1] Univ Fed Mato Grosso do Sul, Curso Mestrado Doencas Infecciosas & Parasitarias, Campo Grande, MS, Brazil

[2] Univ Fed Mato Grosso do Sul, Dept Tecnol Alimentos & Saude Publ, Campo Grande, MS, Brazil

[3] Univ Fed Mato Grosso do Sul, Dept Clin Med, Campo Grande, MS, Brazil

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2009年 / 42卷 / 06期

关键词：

Dengue; Leukopenia; Thrombocytopenia; Lymphocytosis; VIRUS-INFECTION; LYMPHOCYTES; FEVER;

D O I：

10.1590/S0037-86822009000600014

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Dengue is a neglected disease with high morbidity and mortality among children and adults that occurs mainly in tropical and subtropical regions. The objective of this study was to evaluate hematological changes in patients with clinical manifestations of dengue. Medical records relating to 543 cases of dengue virus 3 that occurred during the 2007 epidemic in Campo Grande, Mato Grosso do Sul, were studied. Cases of classic dengue predominated (90.2%), with mild clinical manifestations lacking complications. The main hematological findings were leukopenia (68.3%), thrombocytopenia (66.5%), lymphocytopenia (67.2%) and atypical lymphocytes (67%). in dengue hemorrhagic fever, thrombocytopenia was more prolonged and the number of atypical lymphocytes was higher, while the other hematological abnormalities presented daily evolution similar to those in classic dengue. The hematological changes observed in dengue present according to the clinical course of the disease and its severity.

引用

页码：682 / 685

页数：4

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