Report of a Successful Treatment of Pulmonary Cunninghamella bertholletiae Infection With Liposomal Amphotericin and Posaconazole in a Child With GvHD and Review of the Literature

被引:22
作者
Garbino, Jorge [1 ]
Myers, Catherine [2 ]
Ambrosioni, Juan [1 ]
Gumy-Pause, Fabienne [2 ]
机构
[1] Univ Hosp Geneva, Div Infect Dis, Dept Internal Med, CH-1211 Geneva 14, Switzerland
[2] Univ Hosp Geneva, Dept Paediat, Div Paediat Med, CH-1211 Geneva 14, Switzerland
关键词
Cunninghamella bertholletiae; posaconazole; zygomycosis; GVHD; antifungal treatment; ZYGOMYCOSIS; FLUCONAZOLE; ITRACONAZOLE; PROPHYLAXIS; PATIENT;
D O I
10.1097/MPH.0b013e3181c2bdce
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Zygomycosis is an emerging, opportunistic fungal infection particularly affecting immunocomprised patients. We report the case of a 10-year-old girl who developed pulmonary zygomycosis because of Cunninghamella bertholletiae 1 year after undergoing bone marrow transplantation complicated with severe cutaneous and digestive graft-versus-host disease. Treatment with surgery and liposomal amphotericin B followed by posaconazole successfully treated the infection.
引用
收藏
页码:85 / 87
页数:3
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