Validity and Reliability of a French Version of Reflux Symptom Index

Objective. To develop a French version of the Reflux Symptom Index (Fr-RSI) and to assess its internal consistency, reliability, and clinical validity. Study Design. Controlled, prospective trial. Materials and Methods. Forty-four patients with a reflux finding score > 7 and an Fr-RSI > 13 were enrolled and treated with 20 mg of pantoprazole twice daily and diet changes for 3 months. Ninety asymptomatic subjects were also included in the study. To assess reliability, Fr-RSI was completed twice within a 7-day period. Validity was assessed by comparing Fr-RSI scores with scores from the Voice Handicap Index (VHI) in 24 of 44 patients, at baseline and at 3 months posttherapy. Results. The mean values of Fr-RSI at baseline and after 7 days were 20.17 +/- 5.76 and 19.75 +/- 7.08, respectively, for patients with laryngopharyngeal reflux (LPR) and 4.02 +/- 3.49 and 3.71 +/- 3.82, respectively, for controls. The test-retest reliability was high in patients with LPR (r(BP) = 0.78) and in healthy subjects (r(BP) = 0.80). Cronbach's alpha was 0.85, indicating high internal consistency. The mean Fr-RSI score significantly improved from a baseline of 20.17 +/- 5.76 to 5.58 +/- 3.65 after 3 months of treatment (P = 0.001), and the initial mean VHI total score significantly improved from 20.29 +/- 19.62 to 12.87 +/- 12.04 after treatment (P = 0.029), indicating validity of the results. However, of the subcategories of the VHI, only the mean physical score improved from a baseline of 11.19 +/- 9.22 to 7.35 +/- 5.96 after treatment (P = 0.016). Conclusion. The Fr-RSI developed in this study demonstrated both reliability and validity. It can be easily administered to assist in diagnosing and monitoring of LPR in French-speaking patients.