Rapidly progressing mycosis fungoides presenting as follicular mucinosis

被引:46
作者
Bonta, MD
Tannous, ZS
Demierre, MF
Gonzalez, E
Harris, NL
Duncan, LM
机构
[1] Massachusetts Gen Hosp, Dermatopathol Unit, Dept Pathol, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Dept Dermatol, Boston, MA 02114 USA
[3] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA
[4] Harvard Univ, Sch Med, Dept Dermatol, Boston, MA 02115 USA
[5] Boston Univ, Sch Med, Dept Dermatol, Boston, MA 02118 USA
关键词
D O I
10.1067/mjd.2000.107741
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Follicular mucinosis can occur as a primary idiopathic disorder or can arise in association with benign or malignant disease, most notably mycosis fungoides. We describe a patient with an aggressive folliculotropic variant of mycosis fungoides that initially presented as follicular mucinosis with alopecia. One month after the diagnosis of follicular mucinosis, a diagnosis of mycosis fungoides was made, and 3 months later inguinal lymph node involvement with mycosis fungoides developed. A skin biopsy specimen demonstrated prominent follicular mucinosis with folliculotropism of atypical cells and intrafollicular Pautrier's microabscesses. As demonstrated in this case, follicular mucinosis can be a presenting sign of rapidly progressive mycosis fungoides. In our review of follicular mucinosis and its association with mycosis fungoides, we found that the folliculotropic variant of mycosis fungoides appears more commonly to have an aggressive course than classic mycosis fungoides.
引用
收藏
页码:635 / 640
页数:6
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