Incomplete Intestinal Obstruction Caused by a Rare Epithelioid Inflammatory Myofibroblastic Sarcoma of the Colon A Case Report

被引:14
作者
Bai, Yanjun [1 ]
Jiang, Maofen [2 ]
Liang, Wenjie [3 ]
Chen, Feng [3 ]
机构
[1] Zhejiang Univ, Dept Radiol, Hangzhou 310003, Zhejiang, Peoples R China
[2] Zhejiang Univ, Dept Pathol, Peoples Hosp Beilun Dist, Beilun Branch Hosp,Affiliated Hosp 1, Hangzhou 310003, Zhejiang, Peoples R China
[3] Zhejiang Univ, Coll Med, Dept Radiol, Affiliated Hosp 1, 79 Qingchun Rd, Hangzhou 310003, Zhejiang, Peoples R China
关键词
TUMOR; PSEUDOTUMOR; FEATURES; EXPRESSION; RECURRENT; TISSUE;
D O I
10.1097/MD.0000000000002342
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We reported on 1 case of epithelioid inflammatory myofibroblastic sarcoma (EIMS) that occurred in the colon and resulted in an incomplete intestinal obstruction. A 65-year-old male patient presented with abdominal pain without any obvious predisposing cause. He reported a paroxysmal dull pain. Hematochezia occurred occasionally. The symptoms appeared repeatedly and became progressively more aggravated. The patient sought medical advice in our hospital, and his enteroscopy showed colon tumors and an incomplete colonic obstruction. The laboratory examination indicated mild anemia. Plain and enhanced computed tomography (CT) scans showed a large, dumbbell-shaped, soft-tissue mass of 4.1 cm x 9.3 cm in the curved lumen of the descending colon near the spleen. After enhancement, the lesion presented with progressive and uneven enhancement. The boundary between the lesion and parts of the left kidney and spleen was obscured. A small amount of exudation was observed around the lumen, and a slightly enlarged lymph node shadow was observed in the mesangial gap. After each preoperative examination was completed, the tumors invading the spleen and left kidney were excised. Based on the surgical specimen pathological histology and immunohistochemistry, epithelioid inflammatory myofibroblastic sarcoma was diagnosed. Tumor recurrence occurred a short time after excision. EIMS in the abdominal cavity could occur on the intestinal wall, occasionally manifesting as large masses that expand to the inside and the outside of the cavity. It needs to be distinguished from other tumors. Tumor recurrence can easily occur after surgery. Anaplasticlymphoma kinase (ALK) inhibitors are a potential alternative treatment option.
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页数:5
相关论文
共 25 条
[11]   Inflammatory Myofibroblastic Tumors of the Abdomen as Mimickers of Malignancy: Imaging Features in Nine Children [J].
Kim, Su Jin ;
Kim, Woo Sun ;
Cheon, Jung-Eun ;
Shin, Su-Mi ;
Youn, Byung Jae ;
Kim, In-One ;
Yeon, Kyung Mo .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2009, 193 (05) :1419-1424
[12]   Pulmonary inflammatory pseudotumor (inflammatory myofibroblastic tumor) - CT features with pathologic correlation [J].
Kim, TS ;
Han, J ;
Kim, GY ;
Lee, KS ;
Kim, H ;
Kim, J .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 2005, 29 (05) :633-639
[13]   Epithelioid inflammatory myofibroblastic sarcoma arising in the pleural cavity [J].
Kozu Y. ;
Isaka M. ;
Ohde Y. ;
Takeuchi K. ;
Nakajima T. .
General Thoracic and Cardiovascular Surgery, 2014, 62 (3) :191-194
[14]   Epithelioid Inflammatory Myofibroblastic Sarcoma Responsive to Surgery and an ALK Inhibitor in a Patient with Panhypopituitarism [J].
Kurihara-Hosokawa, Kotomi ;
Kawasaki, Isao ;
Tamai, Anna ;
Yoshida, Yoko ;
Yakushiji, Yosuke ;
Ueno, Hiroki ;
Fukumoto, Mariko ;
Fukushima, Hiroko ;
Inoue, Takeshi ;
Hosoi, Masayuki .
INTERNAL MEDICINE, 2014, 53 (19) :2211-2214
[15]   From the archives of the AFIP: Abdominal neoplasms in patients with neurofibromatosis type 1: Radiologic-pathologic correlation [J].
Levy, AD ;
Patel, N ;
Dow, N ;
Abbott, RM ;
Miettinen, M ;
Sobin, LH .
RADIOGRAPHICS, 2005, 25 (02) :455-480
[16]   Inflammatory myofibroblastic tumor with RANBP2 and ALK gene rearrangement: a report of two cases and literature review [J].
Li, Jian ;
Yin, Wei-hua ;
Takeuchi, Kengo ;
Guan, Hong ;
Huang, Yu-hua ;
Chan, John K. C. .
DIAGNOSTIC PATHOLOGY, 2013, 8
[17]  
MAIER HC, 1987, CANCER-AM CANCER SOC, V60, P1073, DOI 10.1002/1097-0142(19870901)60:5<1073::AID-CNCR2820600524>3.0.CO
[18]  
2-O
[19]   Epithelioid Inflammatory Myofibroblastic Sarcoma: An Aggressive Intra-abdominal Variant of Inflammatory Myofibroblastic Tumor With Nuclear Membrane or Perinuclear ALK [J].
Marino-Enriquez, Adrian ;
Wang, Wei-Lien ;
Roy, Angshumoy ;
Lopez-Terrada, Dolores ;
Lazar, Alexander J. F. ;
Fletcher, Christopher D. M. ;
Coffin, Cheryl M. ;
Hornick, Jason L. .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2011, 35 (01) :135-144
[20]   INFLAMMATORY FIBROSARCOMA OF THE MESENTERY AND RETROPERITONEUM - A TUMOR CLOSELY SIMULATING INFLAMMATORY PSEUDOTUMOR [J].
MEIS, JM ;
ENZINGER, FM .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1991, 15 (12) :1146-1156