Dietary consumption of advanced glycation end products and risk of metabolic syndrome

被引：50

作者：

Angoorani, Pooneh ^{[1
]}

Ejtahed, Hanieh-Sadat ^{[2
,3
]}

Mirmiran, Parvin ^{[1
,4
]}

Mirzaei, Sahar ^{[1
]}

Azizi, Fereidoun ^{[5
]}

机构：

[1] Shahid Beheshti Univ Med Sci, Nutr & Endocrine Res Ctr, Res Inst Endocrine Sci, Box 19395-4741, Tehran, Iran

[2] Univ Tehran Med Sci, Endocrinol & Metab Mol Cellular Sci Inst, Obes & Eating Habits Res Ctr, Tehran, Iran

[3] Univ Tehran Med Sci, Endocrinol & Metab Res Ctr, Endocrinol & Metab Clin Sci Inst, Tehran, Iran

[4] Shahid Beheshti Univ Med Sci, Natl Nutr & Food Technol Res Inst, Fac Nutr Sci & Food Technol, Dept Clin Nutr & Dietet, Tehran, Iran

[5] Shahid Beheshti Univ Med Sci, Res Inst Endocrine Sci, Endocrine Res Ctr, Tehran, Iran

来源：

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION | 2016年 / 67卷 / 02期

关键词：

Abdominal obesity; dietary AGEs; hypertriglyceridemia; metabolic syndrome; obesity; OXIDATIVE STRESS; NUTRITION TRANSITION; SOLUBLE RECEPTOR; VISCERAL FAT; RAGE; ENDPRODUCTS; QUESTIONNAIRE; GLYCOTOXINS; DISEASE; ACCUMULATION;

D O I：

10.3109/09637486.2015.1137889

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Metabolic syndrome (MetS) is a complex disorder which has become one of the major public health challenges worldwide. This study was conducted to evaluate the association between dietary advanced glycation end products (AGEs) and risk of MetS and its components. This cross-sectional study was conducted in a representative sample of 5848 adults, aged 19-70 years. Daily consumption of carboxymethyl lysine, a major type of AGEs, was determined using a validated semi-quantitative food frequency questionnaire. Across increasing trend of AGEs consumption, the percentage of fat intake increased and that of carbohydrate significantly decreased (p<0.001). Subjects in the highest (>10506 kU/d) compared to the lowest (<6673 kU/d) quartile category of AGEs had higher risk of abdominal obesity (OR: 1.19, 95% CI: 1.01-1.39) and hypertriglyceridemia (OR: 1.26, 95% CI: 1.07-1.49). Therefore, recommendation on restriction of AGEs intake could be a practical approach to prevent metabolic abnormalities.

引用

页码：170 / 176

页数：7

共 48 条

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[2]

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