Five cases of vector-borne Francisella tularensis holarctica infections in south-western Germany and genetic diversity

被引:16
作者
Borde, Johannes P. [1 ,3 ]
Zange, Sabine [2 ]
Antvverpen, Markus H. [2 ]
Georgi, Enrico [2 ]
von Buttlar, Heiner [2 ]
Kern, Winfried V. [3 ]
Rieg, Siegbert [3 ]
机构
[1] Gesundheitszentrum Oberkirch, Praxis Dr J Borde, Marktpl 8, D-77704 Oberkirch, Germany
[2] Bundeswehr Inst Microbiol, Neuherbergstr 11, D-80937 Munich, Germany
[3] Univ Freiburg, Fac Med, Med Ctr, Div Infect Dis,Dept Med 2, D-79106 Freiburg, Germany
关键词
Tularemia; Zoonotic disease; Germany; Francisella tularensis; Tick-borne; MLVA; TULAREMIA; TRANSMISSION; TICKS;
D O I
10.1016/j.ttbdis.2017.06.009
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Tularemia is a rare zoonotic disease in Germany. Francisella tularensis has been isolated previously from ticks in southern Germany underscoring the importance of ticks (Ixodes ricinus) in tularemia transmission, but there have been only few reports from this region with single cases or small case series of tick-borne transmissions of tularemia. We report five cases of non-game animal associated tularemia diagnosed from 2010 to 2016 in southwestern Germany Baden-Wuerttemberg. Our case series and molecular typing (MLVA) results add published clinical experience to this underdiagnosed disease and consolidate previous findings regarding tick-borne transmission of tularemia and phylogenetic diversity in Germany.
引用
收藏
页码:808 / 812
页数:5
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