Facile synthesis and antibacterial evaluation of poly(acrylamide-co-(-cyclodextrin))/silver nanocomposite

Hydrogel/silver nanocomposites have shown immense potential in many biological applications. In this article, a facile method to synthesize poly(acrylamide-co-(-cyclodextrin))/silver nanocomposites is reported. The silver nanoparticles were in situ synthesized accompanying with the formation of poly(acrylamide-co-(-cyclodextrin)) hydrogel by gamma irradiation without additional reducing and stabilizing agents. In addition, the nanocomposites were prepared under ambient conditions. The formation of silver nanoparticles was confirmed by ultraviolet used to characterize the structure and composition of the synthetic nanocomposites. Transmission electron microscope verified the formation and homogeneous distribution of silver nanoparticles in the hydrogel matrix. The hybrid hydrogel exhibited excellent water-swelling properties, which could be controlled by varying the mass ratio of acrylamide (AM) to -cyclodextrin (-CD) in the hydrogel. Furthermore, the poly(acrylamide-co-(-cyclodextrin))/silver nanocomposites were found to be effective in inhibiting the growth of both Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus. POLYM. COMPOS., 37:1480-1487, 2016. (c) 2014 Society of Plastics Engineers