Recent development in fluorescent probes based on attacking of double bond and masking of functional group

被引:68
作者
Ahmed, Nadeem [1 ]
Zareen, Wajeeha [1 ]
Ye, Yong [1 ]
机构
[1] Zhengzhou Univ, Coll Chem, Phosphorus Chem Engn Res Ctr Henan Prov, Zhengzhou 450002, Peoples R China
基金
美国国家科学基金会;
关键词
Fluorescent probes; Hypochlorous acid; Peroxynitirite; Biothiols; Michael addition; IMAGING ENDOGENOUS PEROXYNITRITE; TURN-ON PROBE; LARGE STOKES SHIFT; LIVING CELLS; HYDROGEN-PEROXIDE; FAR-RED; H2S; MITOCHONDRIA; DESIGN; FLUOROPHORE;
D O I
10.1016/j.cclet.2021.12.092
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The works on the procedure of fluorescent sensors for the detection of biological analytes are extremely momentous. Among diverse analytical approaches, fluorescence is the most eye-catching due to its high sensitivity, selectivity, rapidity, robustness, ease of measurement and non-destructive approaches. Herein, we show different fluorescent probes synthesized for estimation and detection of biological analytes (H2S, SO32-/HSO3, H2O2, HOCl, HNO, ONOO-). These probes were constructed by masking the functional groups (hydroxyl and amino) of fluorophore and formation of active C=C, C=N, C=O and N=N for specific analytes. In this review we concentrate on synthesis of the probe, their photophysical properties and applications to biological studies. (C) 2022 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.
引用
收藏
页码:2765 / 2772
页数:8
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