According to GEM model, it constructs the evaluation index system of e-commerce industry cluster competitiveness, using AHP analysis method to determine relevant index weight, to make quantitative evaluation of Wuhan e-commerce industry cluster competitiveness. The empirical study finds that Wuhan e-commerce industry cluster competitiveness is over the national average level, in the middle and upper level. The basic factor score is the highest and market factor score is the second, and enterprise factor score is relatively lower, illustrating that industry cluster competitiveness level is to be improved. For the empirical analysis results, it proposes the countermeasures of improving Wuhan e-commerce industry cluster competitiveness.