An Extremely Rare Case of Rectal Signet Ring Cell Carcinoma

被引:4
作者
Seog, Woo Jin [1 ]
Dhruv, Samyak [2 ]
Atodaria, Kuldeepsinh P. [3 ]
Polavarapu, Abhishek [4 ]
机构
[1] Touro Coll Osteopath Med, New York, NY USA
[2] MedStar St Marys Hosp, Leonardtown, MD 20650 USA
[3] Abington Hlth, Abington, PA USA
[4] Norman Reg Hlth Syst, Norman, OK USA
关键词
Signet ring cell carcinoma; Rectum; Colorectal cancer; Chemotherapy; CLINICAL-SIGNIFICANCE; COLORECTAL-CARCINOMA; COLON; OUTCOMES; ADENOCARCINOMA;
D O I
10.14740/gr1516
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Signet ring cell carcinoma of the rectum is a rare variant of colorectal cancer. When found, it is often diagnosed in late stages and has poor prognosis. This case depicts a patient with a history of Crohn's disease who presented to the hospital for perirectal abscesses. During the evaluation of both the abscesses and Crohn's disease, he was found to have stage IV adenocarcinoma with signet ring cell features. The patient was started on chemotherapy before surgical resection was considered, however, showed little response. The patient's family eventually pursued hospice care with comfort measures only. Colorectal signet ring cell carcinoma is rare but has poor prognosis as it is diagnosed generally at late and advanced stages. There is a need for more research in earlier detection of these rare cancers.
引用
收藏
页码:106 / 111
页数:6
相关论文
共 28 条
  • [21] Clinical significance of signet-ring cells in colorectal mucinous adenocarcinoma
    Sung, Chang Okh
    Seo, Jin Won
    Kim, Kyoung-Mee
    Do, In-Gu
    Kim, Seon Woo
    Park, Cheol-Keun
    [J]. MODERN PATHOLOGY, 2008, 21 (12) : 1533 - 1541
  • [22] Signet ring colorectal carcinoma: Do we need to improve the treatment algorithm?
    Tamhankar, Anup Sunil
    Ingle, Parag
    Engineer, Reena
    Bal, Munita
    Ostwal, Vikas
    Saklani, Avanish
    [J]. WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2016, 8 (12) : 819 - 825
  • [23] Colorectal Cancer and Nutrition
    Thanikachalam, Kannan
    Khan, Gazala
    [J]. NUTRIENTS, 2019, 11 (01)
  • [24] Tung SY, 1996, AM J GASTROENTEROL, V91, P2195
  • [25] Signet-ring cell change versus signet-ring cell carcinoma - A comparative analysis
    Wang, K
    Weinrach, D
    Lal, A
    Musunuri, S
    Ramirez, J
    Ozer, O
    Keh, P
    Rao, MS
    [J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2003, 27 (11) : 1429 - 1433
  • [26] The Characteristics and Prognostic Effect of E-Cadherin Expression in Colorectal Signet Ring Cell Carcinoma
    Wang, Renjie
    Ma, Xiaoji
    Li, Yaqi
    He, Yiping
    Huang, Dan
    Cai, Sanjun
    Peng, Junjie
    [J]. PLOS ONE, 2016, 11 (08):
  • [27] Clinicopathological characteristics and survival in colorectal signet ring cell carcinoma: a population-based study
    Yang, Luo-luo
    Wang, Min
    He, Ping
    [J]. SCIENTIFIC REPORTS, 2020, 10 (01)
  • [28] Zhou J L, 2020, Zhonghua Zhong Liu Za Zhi, V42, P897, DOI 10.3760/cma.j.cn112152-20200228-00142