Zinc(II)-induced control of the internalization of a near-infrared fluorescent probe by live cells

被引:7
作者
Koenig, Sandra G. [1 ]
Oez, Simin [1 ]
Kraemer, Roland [1 ]
机构
[1] Heidelberg Univ, Anorgan Chem Inst, Neuenheimer Feld 270, D-69120 Heidelberg, Germany
关键词
PANCREATIC BETA-CELLS; ZINC; CANCER; LOCALIZATION;
D O I
10.1039/c6mb00105j
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We describe zinc-promoted cellular uptake of a near-infrared fluorophore modified with a terpyridine ligand. In response to varying concentrations of exogenous zinc(II), we observed increasing cellular uptake in live HeLa cells as well as other cell lines, whereas only negligible staining was detected in the absence of zinc(II).
引用
收藏
页码:1114 / 1117
页数:4
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