Growth regulation by insulin-like growth factor-I in fish

被引:320
作者
Moriyama, S
Ayson, FG
Kawauchi, H [1 ]
机构
[1] Kitasato Univ, Sch Fisheries Sci, Mol Endocrinol Lab, Sanriku, Iwate 0220101, Japan
[2] SEAFDEC AQD, Iloilo, Philippines
关键词
fish; growth; insulin-like growth factor; structure; function;
D O I
10.1271/bbb.64.1553
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Insulin-like growth factor-I (IGF-I) is a mitogenic polypeptide that plays an essential role in the regulation of development and somatic growth of vertebrates, mainly by mediating growth hormone actions. It has clearly been established that the structure of IGF-I and its biological function has been highly conserved among vertebrates. In this paper, we review the recent developments in the molecular, biochemical, and physiological properties of ICF-I in fish.
引用
收藏
页码:1553 / 1562
页数:10
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