Malignant Hypertension: Current Perspectives and Challenges

被引：47

作者：

Boulestreau, Romain ^{[1
,2
,3
,4
]}

van den Born, Bert-Jan H. ^{[5
,6
]}

Lip, Gregory Y. H. ^{[7
,8
,9
]}

Gupta, Ajay ^{[10
,11
]}

机构：

[1] Bordeaux Univ Hosp, European Excellence Hypertens Ctr, Cardiol Dept, Bordeaux, France

[2] Pau Hosp, Pau, France

[3] INSERM Unit 1034, Pessac, France

[4] INI CRCT Network, Nancy, France

[5] Amsterdam UMC, Amsterdam Cardiovasc Sci, Dept Internal Med, Amsterdam, Netherlands

[6] Amsterdam UMC, Amsterdam Cardiovasc Sci, Dept Publ Hlth, Amsterdam, Netherlands

[7] Univ Liverpool, Liverpool Ctr Cardiovasc Sci, Liverpool, Merseyside, England

[8] Liverpool Heart & Chest Hosp, Liverpool, Merseyside, England

[9] Aalborg Univ, Dept Clin Med, Aalborg, Denmark

[10] Queen Mary Univ London, William Harvey Res Inst, London, England

[11] Barts Hlth NHS Trust, St Bartholomews & Royal London Hosp, London, England

来源：

JOURNAL OF THE AMERICAN HEART ASSOCIATION | 2022年 / 11卷 / 07期

关键词：

basic science; clinical research; hypertensive emergency; malignant hypertension;

D O I：

10.1161/JAHA.121.023397

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Malignant hypertension is a hypertensive emergency, with rapid disease progression and poor prognosis. Although recognized as a separate entity more than a century ago, significant knowledge gaps remain about its pathogenesis and treatment. This narrative review summarizes current viewpoints, research gaps, and challenges with a view to pooling future efforts at improving treatment and prognosis.

引用

页数：5

共 19 条

[1] Mortality and Cardiovascular Risk in Patients With a History of Malignant Hypertension: A Case-Control Study [J].

Amraoui, Fouad ;

Van der Hoeven, Niels V. ;

Van Valkengoed, Irene G. M. ;

Vogt, Liffert ;

Van den Born, Bert-Jan H. .

JOURNAL OF CLINICAL HYPERTENSION, 2014, 16 (02) :122-126

[2] From malignant hypertension to hypertension-MOD: a modern definition for an old but still dangerous emergency [J].

Cremer, A. ;

Amraoui, F. ;

Lip, G. Y. H. ;

Morales, E. ;

Rubin, S. ;

Segura, J. ;

Van den Born, B. J. ;

Gosse, P. .

JOURNAL OF HUMAN HYPERTENSION, 2016, 30 (08) :463-466

[3]

DRANOV J, 1974, ARCH INTERN MED, V133, P791

[4] The pharmacological management of malignant hypertension [J].

Gosse, Philippe ;

Boulestreau, Romain ;

Brockers, Camille ;

Puel, Charlotte ;

Rubin, Sebastien ;

Cremer, Antoine .

JOURNAL OF HYPERTENSION, 2020, 38 (11) :2325-2330

[5] Practice patterns, outcomes, and end-organ dysfunction for patients with acute severe hypertension: The Studying the Treatment of Acute hyperTension (STAT) Registry [J].

Katz, Jason N. ;

Gore, Joel M. ;

Amin, Alpesh ;

Anderson, Frederick A. ;

Dasta, Joseph F. ;

Ferguson, James J. ;

Kleinschmidt, Kurt ;

Mayer, Stephan A. ;

Multz, Alan S. ;

Peacock, W. Frank ;

Peterson, Eric ;

Pollack, Charles ;

Sung, Gene Yong ;

Shorr, Andrew ;

Varon, Joseph ;

Wyman, Allison ;

Emery, Leigh A. ;

Granger, Christopher B. .

AMERICAN HEART JOURNAL, 2009, 158 (04) :599-U23

[6] The syndrome of malignant hypertension [J].

Keith, NM ;

Wagener, HP ;

Kernohan, JW .

ARCHIVES OF INTERNAL MEDICINE, 1928, 41 (02) :141-188

[7] Classification of hypertension and clinical differentiation of the malignant type [J].

Keith, NM .

AMERICAN HEART JOURNAL, 1927, 2 (06) :597-608

[8] HYPERTENSIVE AND RENAL EFFECTS OF CHRONIC LOW-LEVEL INTRA-RENAL ANGIOTENSIN INFUSION IN THE DOG [J].

LOHMEIER, TE ;

COWLEY, AW .

CIRCULATION RESEARCH, 1979, 44 (02) :154-160

[9]

National Guideline Centre (UK), 2019, NBK547161

[10] Funduscopy: Yes or no? Hypertensive emergencies and retinopathy in the emergency care setting; a retrospective cohort study [J].

Nijskens, Charlotte M. ;

Veldkamp, Saskia R. ;

Van Der Werf, Dymph J. ;

Boonstra, Arnold H. ;

Ten Wolde, Marije .

JOURNAL OF CLINICAL HYPERTENSION, 2021, 23 (01) :166-171

← 1 2 →