Intracellular domoic acid production in Pseudo-nitzschia multistriata isolated from the Gulf of Naples (Tyrrhenian Sea, Italy)

被引：46

作者：

Amato, Alberto ^{[1
]}

Luedeking, Alexander ^{[1
]}

Kooistra, Wiebe H. C. F. ^{[1
]}

机构：

[1] Stn Zool A Dohrn, I-80121 Naples, Italy

来源：

TOXICON | 2010年 / 55卷 / 01期

关键词：

Domoic acid; Gulf of Naples; Light; Phosphorus-limitation; Pseudo-nitzschia multistriata; Silica-limitation; Temperature; Toxicity; HARMFUL ALGAL BLOOMS; PHYLOGENETIC-RELATIONSHIPS; SERIATA BACILLARIOPHYCEAE; SILICATE LIMITATION; AMINO-ACID; MULTISERIES; PUNGENS; TOXIN; CYCLE; PSEUDODELICATISSIMA;

D O I：

10.1016/j.toxicon.2009.07.005

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Twenty-six Pseudo-nitzschia multistriata cultures were tested for intracellular domoic acid production and fourteen were found to be toxic. Four suboptimal growth conditions were compared with conditions observed to be optimal to explore possible triggers for intracellular domoic acid production. Silica- and phosphate-limitation and low light treatment induced elevated toxin concentrations whereas high temperature appeared to suppress it. Inheritance of the toxin-production ability was investigated by measuring intracellular toxin content in a total of thirty-nine F-1 strains from two different crosses. Results showed radical differences in domoic acid levels among the F-1 offspring from the same parents. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：157 / 161

页数：5

共 54 条

[1]

Adams NG, 2000, J SHELLFISH RES, V19, P1007

[2] Domoic acid production by Pseudo-nitzschia australis and Pseudo-nitzschia calliantha isolated from North Chile [J].