Direct conversion of aldehydes to amides, tetrazoles, and triazines in aqueous media by one-pot tandem reactions

被引：150
作者：
Shie, JJ [1 ]
Fang, JM [1 ]
机构：
[1] Natl Taiwan Univ, Dept Chem, Taipei 106, Taiwan
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 68卷 / 03期
关键词：
D O I：
10.1021/jo026407z
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A variety of aldehydes reacted with iodine in ammonia water at room temperature to give the nitrile intermediates, which were trapped by addition of hydrogen peroxide, sodium azide, or dicyandiamide to produce their corresponding amides, tetrazoles, and 1,3,5-triazines in modest to high yields. The one-pot tandem reactions were conducted in water media, and the products were obtained simply by extraction or filtration.
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页码：1158 / 1160
页数：3
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