Anti-TB activity of Evodia elleryana bark extract

被引：5

作者：

Barrows, Louis R.

Powan, Emma

Pond, Christopher D.

Matainaho, Teatulohi

机构：

[1] Univ Utah, Coll Pharm, Dept Pharmacol & Toxicol, Salt Lake City, UT 84112 USA

[2] Univ Papua New Guinea, Sch Med & Hlth Sci, Discipline Pharmacol, Boroko, Papua N Guinea

来源：

FITOTERAPIA | 2007年 / 78卷 / 03期

关键词：

Evodia elleryana; TB; Mycobacterium tuberculosis;

D O I：

10.1016/j.fitote.2006.12.001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

An ethyl acetate extract of bark from Evodia elleryana produced significant growth inhibition of Mycobacterium tuberculosis at concentrations only minimally inhibitory to human T cells. The crude extract yielded 95% inhibition of TB at 50 mu g/ml. The crude extract yielded 29% growth inhibition of human T-cells in culture at that concentration. (C) 2007 Elsevier B.V. All rights reserved.

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收藏

页码：250 / 252

页数：3

相关论文

共 11 条

[1] Quinolone alkaloids from Evodia rutaecarpa:: a potent new group of antimycobacterial compounds [J].

Adams, M ;

Wube, AA ;

Bucar, F ;

Bauer, R ;

Kunert, O ;

Haslinger, E .

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2005, 26 (03) :262-264

[2]

Foongladda S, 2002, INT J TUBERC LUNG D, V6, P1118

[3] Rapid, low-technology MIC determination with clinical Mycobacterium tuberculosis isolates by using the microplate Alamar Blue assay [J].

Franzblau, SG ;

Witzig, RS ;

McLaughlin, JC ;

Torres, P ;

Madico, G ;

Hernandez, A ;

Degnan, MT ;

Cook, MB ;

Quenzer, VK ;

Ferguson, RM ;

Gilman, RH .

JOURNAL OF CLINICAL MICROBIOLOGY, 1998, 36 (02) :362-366

[4] Highly selective antibacterial activity of novel alkyl quinolone alkaloids from a Chinese herbal medicine, Gosyuyu (Wu-Chu-Yu), against Helicobacter pylori in vitro [J].

Hamasaki, N ;

Ishii, E ;

Tominaga, K ;

Tezuka, Y ;

Nagaoka, T ;

Kadota, S ;

Kuroki, T ;

Yano, I .

MICROBIOLOGY AND IMMUNOLOGY, 2000, 44 (01) :9-15

[5] FUROQUINOLINE ALKALOIDS FROM EVODIA ELLERYANA F MUELL . STRUCTURE OF EVELLERINE [J].

JOHNS, SR ;

LAMBERTON, JA ;

SIOUMIS, AA .

AUSTRALIAN JOURNAL OF CHEMISTRY, 1968, 21 (07) :1897-+

[6] Antimicrobial activity of Evodia elleryana [J].

Khan, MR ;

Kihara, M ;

Omoloso, AD .

FITOTERAPIA, 2000, 71 (01) :72-74

[7] SOME NATURALLY OCCURRING DIMETHYLCHROMENES .2. ALLOEVODIONE [J].

KIRBY, KD ;

SUTHERLAND, MD .

AUSTRALIAN JOURNAL OF CHEMISTRY, 1956, 9 (03) :411-415

[8] BACTERIOSTATIC HETEROCYCLES FROM EUODIA-LUNU-ANKENDA [J].

MANANDHAR, MD ;

HUSSAINI, FA ;

KAPIL, RS ;

SHOEB, A .

PHYTOCHEMISTRY, 1985, 24 (01) :199-200

[9] The anti-neoplastic and novel topoisomerase II-mediated cytotoxicity of neoamphimedine, a marine pyridoacridine [J].

Marshall, KM ;

Matsumoto, SS ;

Holden, JA ;

Concepción, GP ;

Tasdemir, D ;

Ireland, CM ;

Barrows, LR .

BIOCHEMICAL PHARMACOLOGY, 2003, 66 (03) :447-458

[10] RAPID COLORIMETRIC ASSAY FOR CELLULAR GROWTH AND SURVIVAL - APPLICATION TO PROLIFERATION AND CYTO-TOXICITY ASSAYS [J].

MOSMANN, T .

JOURNAL OF IMMUNOLOGICAL METHODS, 1983, 65 (1-2) :55-63