Analysis of tissue factor positive microparticles

被引：55

作者：

Key, Nigel S. ^{[1
]}

机构：

[1] Univ N Carolina, Dept Med, Div Hematol Oncol, Chapel Hill, NC 27599 USA

来源：

THROMBOSIS RESEARCH | 2010年 / 125卷

关键词：

Tissue factor; Microparticle; Assay; Phosphatidylserine; ENDOTHELIAL-CELLS; IN-VIVO; THROMBUS; PLATELETS; COAGULATION; ACTIVATION; EXPRESSION; MECHANISMS; RELEASE; GROWTH;

D O I：

10.1016/j.thromres.2010.01.035

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There has recently been intense interest in the clinical measurement of tissue factor (TF)-positive microparticles (MPs) in clinical disease states. This interest has been driven by the demonstration of an putative role for circulating TF-positive MPs in animal models of thrombus propagation. Both immunological and functional assays for MP-TF have been described. While each approach has its own advantages and drawbacks, neither has yet been truly established as the 'gold standard'. Heterogeneity of TF-bearing MPs, such as the variable co-expression of surface phosphatidylserine, may determine not only their procoagulant potential, but also additional properties including rate of clearance from the circulation. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：S42 / S45

页数：4

共 46 条

[1] Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure [J].

Amabile, N ;

Guérin, AP ;

Leroyer, A ;

Mallat, Z ;

Nguyen, C ;

Boddaert, J ;

London, GM ;

Tedgui, A ;

Boulanger, CM .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2005, 16 (11) :3381-3388

[2] Induction of microparticle- and cell-associated intravascular tissue factor in human endotoxemia [J].

Aras, O ;

Shet, A ;

Bach, RR ;

Hysjulien, JL ;

Slungaard, A ;

Hebbel, RP ;

Escolar, G ;

Jilma, B ;

Key, NS .

BLOOD, 2004, 103 (12) :4545-4553

[3] The significance of shed membrane particles during programmed cell death in vitro, and in vivo, in HIV-1 infection [J].

Aupeix, K ;

Hugel, B ;

Martin, T ;

Bischoff, P ;

Lill, H ;

Pasquali, JL ;

Freyssinet, JM .

JOURNAL OF CLINICAL INVESTIGATION, 1997, 99 (07) :1546-1554

[4] Procoagulant alveolar microparticles in the lungs of patients with acute respiratory distress syndrome [J].

Bastarache, Julie A. ;

Fremont, Richard D. ;

Kropski, Jonathan A. ;

Bossert, Frederick R. ;

Ware, Lorraine B. .

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2009, 297 (06) :L1035-L1041

[5]

Bevers EM, 1998, BIOL CHEM, V379, P973

[6] Identification and characterization of murine alternatively spliced tissue factor [J].

Bogdanov, VY ;

Kirk, RI ;

Miller, C ;

Hathcock, JJ ;

Vele, S ;

Gazdoiu, M ;

Nemerson, Y ;

Taubman, MB .

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2006, 4 (01) :158-167

[7] Tissue factor activity in whole blood [J].

Butenas, S ;

Bouchard, BA ;

Brummel-Ziedins, KE ;

Parhami-Seren, B ;

Mann, KG .

BLOOD, 2005, 105 (07) :2764-2770

[8] Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation [J].

Chou, J ;

Mackman, N ;

Merrill-Skoloff, G ;

Pedersen, B ;

Furie, BC ;

Furie, B .

BLOOD, 2004, 104 (10) :3190-3197

[9] Lactadherin and clearance of platelet-derived microvesicles [J].

Dasgupta, Swapan K. ;

Abdel-Monem, Hanan ;

Niravath, Polly ;

Le, Anhquyen ;

Bellera, Ricardo V. ;

Langlois, Kimberly ;

Nagata, Shigekazu ;

Rumbaut, Rolando E. ;

Thiagarajan, Perumal .

BLOOD, 2009, 113 (06) :1332-1339

[10] Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall [J].

Day, SM ;

Reeve, JL ;

Pedersen, B ;

Farris, DM ;

Myers, DD ;

Im, M ;

Wakefield, TW ;

Mackman, N ;

Fay, WP .

BLOOD, 2005, 105 (01) :192-198

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