Lichen planopilaris induced by infliximab: A case report

被引:9
作者
McPhie, Meghan L. [1 ]
Wang, Ami [2 ]
Molin, Sonja [3 ,4 ]
Herzinger, Thomas [3 ,4 ]
机构
[1] Queens Univ, Sch Med, Kingston, ON, Canada
[2] Queens Univ, Dept Pathol & Mol Med, Kingston, ON, Canada
[3] Queens Univ, Dept Med, Div Dermatol, Centenary 3-027,166 Brock St, Kingston, ON K7L 5G2, Canada
[4] Hop Hotel Dieu, Centenary 3-027,166 Brock St, Kingston, ON K7L 5G2, Canada
来源
SAGE OPEN MEDICAL CASE REPORTS | 2020年 / 8卷
关键词
Infliximab; TNF-alpha inhibitors; lichenoid dermatitis; lichen planopilaris; drug eruption; ALPHA; ERUPTIONS; PLANUS;
D O I
10.1177/2050313X20901967
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Infliximab is a tumor necrosis factor-alpha inhibitor used to treat a range of inflammatory diseases. Most reports of cutaneous eruptions from tumor necrosis factor-alpha inhibitors have described the paradoxical development of psoriasis or psoriasiform drug reaction. In our report, we present a 31-year-old female with inflammatory bowel disease who developed an unusual lichenoid drug reaction to infliximab involving the hair follicles, resulting in progressive global alopecia. Clinical features and histopathological findings were consistent with drug-induced lichen planopilaris with eosinophils and lichenoid dermatitis.
引用
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页数:4
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