Potential biochemical markers of chronic bronchitis

被引:0
作者
Kurtukov, E. A. [1 ]
Ragino, Yu, I [1 ]
机构
[1] Russian Acad Sci ICG SB RAS, Res Inst Internal & Prevent Med RIIPM, Siberian Branch, 175-1 B Bogatkova Str, Novosibirsk 630089, Russia
来源
BYULLETEN SIBIRSKOY MEDITSINY | 2021年 / 20卷 / 02期
关键词
chronic obstructive pulmonary disease; chronic bronchitis; biochemical markers; tumor necrosis factor alpha; interleukin; 1; 6; 8; 10; tissue factor; type 1 plasminogen activator inhibitor; monocyte chemoattractant protein 1; OBSTRUCTIVE PULMONARY-DISEASE; PLASMINOGEN-ACTIVATOR INHIBITOR-1; MONOCYTE CHEMOATTRACTANT PROTEIN-1; TISSUE FACTOR; SYSTEMIC INFLAMMATION; IL10; POLYMORPHISMS; LUNG-FUNCTION; IN-VITRO; COMPLEMENT; COPD;
D O I
10.20538/1682-0363-2021-2-148-159
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The review systematizes modern data on the biochemical markers that can clarify the nature and the course of chronic bronchitis. The article describes markers associated with bronchopulmonary pathology, such as tumor necrosis factor alpha (TNF alpha), interleukin 1 (IL-1), interleukin 6 (IL-6), interleukin 8 (IL-8), interleukin 10 (IL-10), tissue factor, type 1 plasminogen activator inhibitor (PAI-1), and monocyte chemoattractant protein-1 (MCP-1). For each biomolecule, its properties, functions, direct role in body processes, and associations with bronchopulmonary pathology are described. The use of these markers for early diagnosis of bronchopulmonary pathology and monitoring of the treatment effectiveness is promising and requires further in-depth study.
引用
收藏
页码:148 / 159
页数:12
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