Double spinal dysraphism - Report of three cases

被引:1
作者
Keshavarzi, Sepideh
Nejat, Farideh
Kazemi, Hadi
机构
[1] Univ Tehran Med Sci, Childrens Med Ctr, Dept Neurosurg, Tehran, Iran
[2] Shahed Univ, Dept Pediat, Tehran, Iran
关键词
myelomeningocele; neural tube defect; spinal dysraphism; embryogenesis; pediatric neurosurgery;
D O I
10.3171/ped.2007.106.4.316
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The simultaneous presence of multiple spinal neural tube defects is unusual. There have been only a few of these cases reported in the literature. The authors report on three cases of double spina bifida cystica. One patient had two myelomeningoceles (MMCs) at the cervical and lumbosacral regions, one was noted to have both thoracolumbar and sacral defects, and the third presented with double NIMCs at lumbar and lumbosacral levels. All three neonates in these cases underwent surgical treatment and ventriculoperitoneal (VP) shunt insertion for associated hydrocephalus. One child died at the age of 2 months despite a well-functioning VP shunt. The other two patients had no complications. Current models of neural tube closure do not thoroughly explain the mechanisms of multiple spinal dysraphism, but the multisite closure model provides a better understanding of caudal neural tube closure than other closure-site models.
引用
收藏
页码:316 / 318
页数:3
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