Disc replacement using Pro-Disc C versus fusion: a prospective randomised and controlled radiographic and clinical study

被引:78
作者
Nabhan, A. [1 ]
Ahlhelm, F.
Pitzen, T.
Steudel, W. I.
Jung, J.
Shariat, K.
Steimer, O.
Bachelier, F.
Pape, D.
机构
[1] Univ Saarland, Dept Neurosurg, D-6650 Homburg, Germany
[2] Univ Saarland, Dept Neuroradiol, D-6650 Homburg, Germany
[3] Univ Saarland, Dept Orthoped, D-6650 Homburg, Germany
关键词
spine; bone; fusion; implants; disc replacement; clinical study;
D O I
10.1007/s00586-006-0226-5
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Anterior cervical discectomy and fusion (ACDF) may be considered to be the gold standard for treatment of symptomatic degenerative disc disease within the cervical spine. However, fusion of the segment may result in progressive degeneration of the adjacent segments. Therefore, dynamic stabilization procedures have been introduced. Among these, artificial disc replacement by disc prosthesis seems to be promising. However, to be so, segmental motion must be preserved. This, again, is very difficult to judge and has not yet been proven. The aim of the current study was to first analyse the segmental motion following artificial disc replacement using a disc prosthesis. A second aim was to compare both segmental motion as well as clinical result to the current gold standard (ACDF). This is a prospective controlled study. Twenty-five patients with cervical disc herniation were enrolled and assigned to either study group (receiving a disc prosthesis) or control group (receiving ACDF, using a cage with bone graft and an anterior plate.) Radiostereometric analysis was used to quantify intervertebral motion immediately as well as 3, 6, 12 and 24 weeks postoperatively. Further, clinical results were judged using visual analogue scale and neuro-examination. Cervical spine segmental motion decreased over time in the presence of disc prosthesis or ACDF. However, the loss of segmental motion is significantly higher in the ACDF group, when looked at 3, 6, 12 and 24 weeks after surgery. We observed significant pain reduction in neck and arm postoperatively, without significant difference between both groups (P > 0.05). Cervical spine disc prosthesis preserves cervical spine segmental motion within the first 6 months after surgery. The clinical results are the same when compared to the early results following ACDF.
引用
收藏
页码:423 / 430
页数:8
相关论文
共 44 条
[1]  
[Anonymous], 2004, SPINE J, DOI DOI 10.1016/J.SPINEE.2004.07.026
[2]  
[Anonymous], 2004, SPINE J, DOI DOI 10.1016/J.SPINEE.2004.07.024
[3]   Early results after ProDisc-C cervical disc replacement [J].
Bertagnoli, R ;
Yue, JJ ;
Pfeiffer, F ;
Fenk-Mayer, A ;
Lawrence, JP ;
Kershaw, T ;
Nanieva, R .
JOURNAL OF NEUROSURGERY-SPINE, 2005, 2 (04) :403-410
[4]   ROBINSON ANTERIOR CERVICAL DISKECTOMY AND ARTHRODESIS FOR CERVICAL RADICULOPATHY - LONG-TERM FOLLOW-UP OF 100 AND 22 PATIENTS [J].
BOHLMAN, HH ;
EMERY, SE ;
GOODFELLOW, DB ;
JONES, PK .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1993, 75A (09) :1298-1307
[5]   Use of a novel absorbable hydrogel for augmentation of dural repair: Results of a preliminary clinical study [J].
Boogaarts, JD ;
Grotenhuis, JA ;
Bartels, RHMA ;
Beems, T .
NEUROSURGERY, 2005, 57 (01) :146-151
[6]  
Caspar W, 1998, J SPINAL DISORD, V11, P1
[8]   Surgical experience with an implanted artificial cervical joint [J].
Cummins, BH ;
Robertson, JT ;
Gill, SS .
JOURNAL OF NEUROSURGERY, 1998, 88 (06) :943-948
[9]   ProDisc artificial total lumbar disc replacement: Introduction and early results from the United States clinical trial [J].
Delamarter, RB ;
Fribourg, DM ;
Kanim, LFA ;
Bae, H .
SPINE, 2003, 28 (20) :S167-S175
[10]  
DiAngelo Denis J, 2004, Neurosurg Focus, V17, pE7