SARS-CoV-2 Not Detectable in Ocular Specimens of a Patient with a Past Infection

被引：1

作者：

Felfeli, Tina ^{[1
,2
]}

Mazzulli, Tony ^{[3
,4
]}

Clark, Shawn T. ^{[3
]}

El-Defrawy, Sherif R. ^{[1
,5
]}

Chan, Clara C. ^{[1
,5
,6
,7
]}

机构：

[1] Univ Toronto, Dept Ophthalmol & Vis Sci, 340 Coll St,Suite 400, Toronto, ON M5T 3A9, Canada

[2] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada

[3] Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON, Canada

[4] Univ Hlth Network, Mt Sinai Hosp, Dept Microbiol, Toronto, ON, Canada

[5] Univ Toronto, Kensington Eye Inst, Kensington Vis & Res Ctr, Toronto, ON, Canada

[6] Univ Hlth Network, Toronto Western Hosp, Dept Ophthalmol, Toronto, ON, Canada

[7] St Michaels Hosp, Unity Hlth Toronto, Dept Ophthalmol, Toronto, ON, Canada

来源：

OCULAR IMMUNOLOGY AND INFLAMMATION | 2021年 / 29卷 / 04期

关键词：

Coronavirus; COVID-19; Globe Rupture; Transmission; Viral Shedding;

D O I：

10.1080/09273948.2021.1894458

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: To present a a case study that aims to investigate the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the ocular tissue samples of a patient previously infected with COVID-19 and determine its transmissibility. Study Design: Case Report Results: In this case study, SARS-CoV-2 was not detected in the vitreous and uveal tissue samples by RT-PCR for detection of three gene targets in a patient with a past COVID-19 infection 15 days prior to presention with a globe rupture. Conclusions: Our findings suggest that patients with long-term existence of SARS-CoV-2 at low detectable levels may not have active intraocular viral shedding. This is of particular importance as ophthalmic surgical procedures may potentiate virus spread from patients infected with SARS-CoV-2.

引用

页码：681 / 683

页数：3

共 14 条

[1]

Braga-Mele R., 2020, OPHTHALMOLOGY

[2]

CASAGRE M, 2020, OCUL IMMUNOL INFLAMM, V28

[3]

Chodosh J, 2020, AM ACAD OPHTHALMOL

[4] Correlation between viral RNA shedding and serum antibodies in individuals with coronavirus disease 2019 [J].