Optical molecular imaging in atherosclerosis

被引：4

作者：

Subramanian, Sharath ^{[1
]}

Jaffer, Farouc A. ^{[2
,3
]}

Tawakol, Ahmed ^{[1
,2
,4
]}

机构：

[1] Massachusetts Gen Hosp, Cardiac MR PET CT Program, Div Cardiol, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Cardiovasc Res Ctr, Dept Med, Boston, MA 02114 USA

[3] Massachusetts Gen Hosp, Ctr Mol Imaging Res, Boston, MA 02114 USA

[4] Massachusetts Gen Hosp, Dept Imaging, Boston, MA 02114 USA

来源：

JOURNAL OF NUCLEAR CARDIOLOGY | 2010年 / 17卷 / 01期

关键词：

Atherosclerosis; inflammation; optical imaging; plaque; fluorescence imaging; FIBRONECTIN ED-B; EXTRA-DOMAIN-B; IN-VIVO; MATRIX METALLOPROTEINASES; PLAQUE INSTABILITY; VULNERABLE PLAQUE; INFLAMMATION; NEOVASCULARIZATION; ANGIOGENESIS; APOPTOSIS;

D O I：

10.1007/s12350-009-9175-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Current imaging techniques focus on evaluating the anatomical structure of blood vessel wall and atherosclerotic plaque. These techniques fail to evaluate the biological processes which take place in the vessel wall and inside the plaque. Novel imaging techniques like optical imaging can evaluate the biological and cellular processes inside the plaque and provide information which can be vital for better patient risk stratification. This review highlights the various optical imaging techniques and their application in assessing biological processes in atherosclerosis.

引用

页码：135 / 144

页数：10