Vitamin D: Musculoskeletal health

被引:40
作者
Bhattoa, Harjit Pal [1 ]
Konstantynowicz, Jerzy [2 ]
Laszcz, Natalia [3 ]
Wojcik, Marek [3 ]
Pludowski, Pawel [3 ]
机构
[1] Univ Debrecen, Dept Lab Med, Fac Med, Nagyerdei Krt 98, H-4032 Debrecen, Hungary
[2] Med Univ Bialystok, Dept Pediat Rheumatol Immunol & Metab Bone Dis, Ul Waszyngtona 17, PL-15274 Bialystok, Poland
[3] Childrens Mem Hlth Inst, Dept Biochem Radioimmunol Expt Med, Warsaw, Poland
关键词
Vitamin D; Bone; Muscle; Osteoporosis; Falls; Sarcopenia; RANDOMIZED CONTROLLED-TRIAL; P450C24; CYP24; PROMOTER; BONE-MINERAL DENSITY; D-RECEPTOR GENE; D SUPPLEMENTATION; HIP FRACTURE; CALCIUM SUPPLEMENTATION; MUSCLE STRENGTH; D-DEFICIENCY; DOUBLE-BLIND;
D O I
10.1007/s11154-016-9404-x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Perhaps the role of Vitamin D supplementation has been most exhaustively studied in calcium absorption, skeletal wellbeing, muscular potency, balance and risk of falling. Nonetheless, new data has emerged and the recent research on sarcopenia makes the topic increasingly interesting. Given the socioeconomic burden of the musculoskeletal consequences of hypovitaminosis D it is vital to keep abreast with the latest literature in the field. The recommended Vitamin D supplementation dose should suffice to increase the serum 25 hydroxyvitamin D level to 30 ng/mL (75 nmol/L) and this level should be optimally maintained with a maintenance dose, particularly for those diagnosed with osteoporosis.
引用
收藏
页码:363 / 371
页数:9
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