Ochratoxin A acts as a photoactivatable DNA cleaving agent

被引：27

作者：

Gillman, IG ^{[1
]}

Yezek, JM ^{[1
]}

Manderville, RA ^{[1
]}

机构：

[1] Wake Forest Univ, Dept Chem, Winston Salem, NC 27109 USA

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 06期

关键词：

D O I：

10.1039/a708275d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The ability of ochratoxin A to photoinduce DNA cleavage is described; in the presence of DNA the photoreaction yields the non-chlorinated derivative, ochratoxin B, while a hydroquinone derivative is produced under anaerobic conditions.

引用

页码：647 / 648

页数：2

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