Chemotherapy of primary central nervous system lymphoma

被引：0
|
作者：
Delwail, V [1 ]
Bataille, B
机构：
[1] CHU, Serv Hematol & Oncol Med, F-86021 Poitiers, France
[2] CHU La Miletrie, Serv Neurochirurg, F-86021 Poitiers, France
来源：
NEUROCHIRURGIE | 1997年 / 43卷 / 06期
关键词：
brain neoplasm; lymphoma; chemotherapy;
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Effective treatment in primary central nervous system lymphoma remains elusive. Usually high dose methotrexate and/or cytosine arabinoside may improve survival. We report the results of multimodality therapy in 248 patients (SFNC series). The addition of chemotherapy to radiation therapy and high dose methotrexate increased the duration of survival. We demonstrate that the use of anthracyclines in addition to radiation therapy had a significantly favorable impact on survival which is not reported in the Literature. Survival was not longer in patients receiving intrathecal chemotherapy. The efficacy of chemotherapy alone has not been clearly defined.
引用
收藏
页码：380 / 384
页数：5
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