Subacute cutaneous lupus erythematosus in childhood

被引:8
作者
Amato, L [1 ]
Coronella, G [1 ]
Berti, S [1 ]
Moretti, S [1 ]
Fabbri, P [1 ]
机构
[1] Univ Florence, Dept Dermatol Sci, Florence, Italy
关键词
D O I
10.1046/j.1525-1470.2003.03007.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
We report a 7-year-old girl who presented with erythematous-infiltrated, figurate, well-defined lesions over sun-exposed skin and antinuclear and Ro/SSA antibodies. Lupus band test revealed granular IgM and microgranular C3 deposits at the dermoepidermal junction. Histopathologic examination of lesional skin showed orthohyperkeratosis, epidermal atrophy, widespread hydropic degeneration of the epidermal basal cell layer, and a dermal perivascular lymphohistiocytic infiltrate. The clinical, immunopathologic, and histopathologic findings were consistent with the diagnosis of annular-polycyclic variant of subacute cutaneous lupus erythematosus (SCLE). Treatment with hydroxychloroquine cleared the cutaneous lesions. We report this patient because SCLE is extremely rare in childhood, and discuss the two previous cases reported in the literature.
引用
收藏
页码:31 / 34
页数:4
相关论文
共 12 条
[1]   Childhood subacute cutaneous lupus erythematosus associated with homozygous complement 2 deficiency [J].
Buckley, D ;
Barnes, L .
PEDIATRIC DERMATOLOGY, 1995, 12 (04) :327-330
[2]   SUBACUTE CUTANEOUS LUPUS-ERYTHEMATOSUS - CLINICAL, SEROLOGIC, IMMUNOGENETIC, AND THERAPEUTIC CONSIDERATIONS IN 72 PATIENTS [J].
CALLEN, JP ;
KLEIN, J .
ARTHRITIS AND RHEUMATISM, 1988, 31 (08) :1007-1013
[3]   Subacute cutaneous lupus erythematosus versus systemic lupus erythematosus: Diagnostic criteria and therapeutic implications [J].
Chlebus, E ;
Wolska, H ;
Blaszczyk, M ;
Jablonska, S .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1998, 38 (03) :405-412
[4]  
Hood A F, 1985, Clin Dermatol, V3, P36, DOI 10.1016/0738-081X(85)90076-8
[5]   LUPUS-ERYTHEMATOSUS IN CHILDHOOD [J].
LEE, LA ;
WESTON, WL .
DERMATOLOGIC CLINICS, 1986, 4 (01) :151-160
[6]   DUST-LIKE PARTICLES - A SPECIFIC DIRECT IMMUNOFLUORESCENCE PATTERN IN SUB-ACUTE CUTANEOUS LUPUS-ERYTHEMATOSUS [J].
NIEBOER, C ;
TAKDIAMAND, Z ;
VANLEEUWENWALLAU, HE .
BRITISH JOURNAL OF DERMATOLOGY, 1988, 118 (05) :725-729
[7]   Clinical, histological and immunopathological features of 58 patients with subacute cutaneous lupus erythematosus - A review by the Italian Group of Immunodermatology [J].
Parodi, A ;
Caproni, M ;
Cardinali, C ;
Bernacchi, E ;
Fuligni, A ;
De Panfilis, G ;
Zane, C ;
Papini, M ;
Veller, FC ;
Vaccaro, M ;
Fabbri, P .
DERMATOLOGY, 2000, 200 (01) :6-10
[8]   SUBACUTE CUTANEOUS LUPUS-ERYTHEMATOSUS IN CHILDHOOD [J].
SIAMOPOULOUMAVRIDOU, A ;
STEFANOU, D ;
DROSOS, AA .
CLINICAL RHEUMATOLOGY, 1989, 8 (04) :533-537
[9]   SUBACUTE CUTANEOUS LUPUS-ERYTHEMATOSUS - A DECADES PERSPECTIVE [J].
SONTHEIMER, RD .
MEDICAL CLINICS OF NORTH AMERICA, 1989, 73 (05) :1073-1090
[10]   SEROLOGIC AND HLA ASSOCIATIONS IN SUB-ACUTE CUTANEOUS LUPUS-ERYTHEMATOSUS, A CLINICAL SUBSET OF LUPUS-ERYTHEMATOSUS [J].
SONTHEIMER, RD ;
MADDISON, PJ ;
REICHLIN, M ;
JORDON, RE ;
STASTNY, P ;
GILLIAM, JN .
ANNALS OF INTERNAL MEDICINE, 1982, 97 (05) :664-671