Synthesis and antioxidant properties of novel α-tocopherol glycoconjugates

被引：16
|
作者：
Singh, Anil K. [1 ]
Gopu, K. [1 ]
机构：
[1] Indian Inst Technol, Dept Chem, Bombay 400076, Maharashtra, India
来源：
TETRAHEDRON LETTERS | 2010年 / 51卷 / 08期
关键词：
alpha-Tocopherol; Vitamin E; Glycoconjugates; Click chemistry; Antioxidants; Radioproctants; VITAMIN-E; CLICK CHEMISTRY; OXIDATION; ANALOGS;
D O I：
10.1016/j.tetlet.2009.12.078
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Glycoconjugates of alpha-tocopherol (1), synthesized using click chemistry between alpha-tocopherol-azide and glyco-alkynes are solids, have enhanced water solubility and exhibit radical-scavenging activities comparable to 1, as determined by DPPH and lipid peroxidation assay methods. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1180 / 1184
页数：5
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