Fruitful Decades for Canthin-6-ones from 1952 to 2015: Biosynthesis, Chemistry, and Biological Activities

被引：30

作者：

Dai, Jiangkun ^{[1
]}

Li, Na ^{[1
]}

Wang, Junru ^{[1
]}

Schneider, Uwe ^{[2
]}

机构：

[1] Northwest A&F Univ, Coll Sci, Yangling 712100, Shaanxi, Peoples R China

[2] Univ Edinburgh, EaStCHEM Sch Chem, Kings Bldg,David Brewster Rd, Edinburgh EH9 3FJ, Midlothian, Scotland

来源：

MOLECULES | 2016年 / 21卷 / 04期

基金：

中国国家自然科学基金;

关键词：

canthin-6-one; biosynthesis; chemistry; biological activities; BETA-CARBOLINE ALKALOIDS; CHILOPERONE VAR. ANGUSTIFOLIUM; CATALYZED AMIDATION REACTION; NITRIC-OXIDE PRODUCTION; EURYCOMA-LONGIFOLIA; ZANTHOXYLUM-CHILOPERONE; AILANTHUS-ALTISSIMA; 5,5-DISUBSTITUTED 4,5-DIHYDRO-6H-CANTHIN-6-ONES; ANTIPROLIFERATIVE ACTIVITY; ANTIMALARIAL CONSTITUENTS;

D O I：

10.3390/molecules21040493

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this review, more than 60 natural canthin-6-one alkaloids and their structures are considered. The biosynthesis, efficient and classic synthetic approaches, and biological activities of canthin-6-one alkaloids, from 1952 to 2015, are discussed. From an analysis of their structural properties and an investigation of the literature, possible future trends for canthin-6-one alkaloids are proposed. The information reported will be helpful in future research on canthin-6-one alkaloids.

引用

页数：13

共 2 条

[1] Synthesis, in vitro antibacterial activities of a series of 3-N-substituted canthin-6-ones
Dai, Jiang-Kun
Dan, Wen-Jia
Li, Na
Du, Hong-Tao
Zhang, Ji-Wen
Wang, Jun-Ru
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 26 (02) : 580 - 583
[2] Synthesis, Antitumor, Antitrypanosomal and Antileishmanial Activities of Benzo[4,5]canthin-6-ones Bearing the N′-(Substituted benzylidene)-carbohydrazide and N-Alkylcarboxamide Groups at C-2
Bento Leite Silva, Camila Mareco
Garcia, Francielle Pelegrin
da Silva Rodrigues, Jean Henrique
Nakamura, Celso Vataru
Ueda-Nakamura, Tania
Meyer, Emerson
Tasca Gois Ruiz, Ana Lucia
Foglio, Mary Ann
de Carvalho, Joao Ernesto
da Costa, Willian Ferreira
Sarragiotto, Maria Helena
CHEMICAL & PHARMACEUTICAL BULLETIN, 2012, 60 (11) : 1372 - 1379

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