Malaria transmission-blocking vaccines: the bonus of effective malaria control

被引：33
作者：
Sauerwein, Robert W. [1 ]
机构：
[1] Radboud Univ Nijmegen, Med Ctr, Dept Med Microbiol, NL-6500 HB Nijmegen, Netherlands
来源：
MICROBES AND INFECTION | 2007年 / 9卷 / 06期
关键词：
malaria; transmission; vaccines;
D O I：
10.1016/j.micinf.2007.02.011
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Reduction of transmission is important for effective malaria control. Standard microscopic detection grossly underestimates the human transmission reservoir. Malaria transmission intensity is defined by local and focal conditions. Transmission-blocking vaccines may be effective by directly targeting identified hot spots of transmission. (C) 2007 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：792 / 795
页数：4
相关论文
共 28 条
  • [1] Dynamics of P-falciparum gametocytemia in symptomatic patients in an area of intense perennial transmission in Tanzania
    Akim, NIJ
    Drakeley, C
    Kingo, T
    Simon, B
    Senkoro, K
    Sauerwein, RW
    [J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2000, 63 (3-4) : 199 - 203
  • [2] Spreading the seeds of million-murdering death : metamorphoses of malaria in the mosquito
    Baton, LA
    Ranford-Cartwright, LC
    [J]. TRENDS IN PARASITOLOGY, 2005, 21 (12) : 573 - 580
  • [3] Field epidemiological studies on malaria in a low endemic area in the Philippines
    Belizario, VY
    Saul, A
    Bustos, MDG
    Lansang, MA
    Pasay, CJ
    Gatton, M
    Salazar, NP
    [J]. ACTA TROPICA, 1997, 63 (04) : 241 - 256
  • [4] HIGH HUMAN MALARIAL INFECTIVITY TO LABORATORY-BRED ANOPHELES-GAMBIAE IN A VILLAGE IN BURKINA-FASO
    BOUDIN, C
    OLIVIER, M
    MOLEZ, JF
    CHIRON, JP
    AMBROISETHOMAS, P
    [J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1993, 48 (05) : 700 - 706
  • [5] Moderate effect of artemisinin-based combination therapy on transmission of Plasmodium falciparum
    Bousema, JT
    Schneider, P
    Gouagna, LC
    Drakeley, CJ
    Tostmann, A
    Houben, R
    Githure, JI
    Ord, R
    Sutherland, CJ
    Omar, SA
    Sauerwein, RW
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2006, 193 (08) : 1151 - 1159
  • [6] Sexual-stage antibody responses to P-falciparum in endemic populations
    Bousema, JT
    Drakeley, CJ
    Sauerwein, RW
    [J]. CURRENT MOLECULAR MEDICINE, 2006, 6 (02) : 223 - 229
  • [7] Plasmodium falciparum gametocyte carriage in asymptomatic children in western Kenya -: art. no. 18
    Bousema, JT
    Gouagna, LC
    Drakeley, CJ
    Meutstege, AM
    Okech, BA
    Akim, INJ
    Beier, JC
    Githure, JI
    Sauerwein, RW
    [J]. MALARIA JOURNAL, 2004, 3 (1)
  • [8] Malaria transmission-blocking vaccines - how can their development be supported?
    Carter, R
    Mendis, KN
    Miller, LH
    Molineaux, L
    Saul, A
    [J]. NATURE MEDICINE, 2000, 6 (03) : 241 - 244
  • [9] Spatial simulation of malaria transmission and its control by malaria transmission blocking vaccination
    Carter, R
    [J]. INTERNATIONAL JOURNAL FOR PARASITOLOGY, 2002, 32 (13) : 1617 - 1624
  • [10] Transmission blocking malaria vaccines
    Carter, R
    [J]. VACCINE, 2001, 19 (17-19) : 2309 - 2314
123