High Prevalence of ST131 Isolates Producing CTX-M-15 and CTX-M-14 among Extended-Spectrum-β-Lactamase-Producing Escherichia coli Isolates from Canada

被引：93

作者：

Peirano, Gisele ^{[1
,2
]}

Richardson, David ^{[4
]}

Nigrin, Jana ^{[5
]}

McGeer, Allison ^{[6
]}

Loo, Vivian ^{[7
]}

Toye, Baldwin ^{[8
]}

Alfa, Michelle ^{[9
]}

Pienaar, Colette ^{[10
]}

Kibsey, Pamela ^{[11
]}

Pitout, Johann D. D. ^{[1
,2
,3
]}

机构：

[1] Univ Calgary, Div Microbiol, Calgary Lab Serv, Calgary, AB T2L 2K8, Canada

[2] Univ Calgary, Dept Pathol & Lab Med, Calgary, AB T2L 2K8, Canada

[3] Univ Calgary, Dept Microbiol & Infect Dis, Calgary, AB T2L 2K8, Canada

[4] William Osler Hlth Ctr, Brampton, ON, Canada

[5] Dynacare Kasper Med Labs, Edmonton, AB, Canada

[6] Mt Sinai Hosp, Toronto, ON M5G 1X5, Canada

[7] Montreal Gen Hosp, Montreal, PQ H3G 1A4, Canada

[8] Ottawa Hosp, Ottawa, ON, Canada

[9] St Boniface Gen Hosp, Diagnost Serv Manitoba, Winnipeg, MB R2H 2A6, Canada

[10] LifeLabs Med Lab Serv, Burnaby, BC, Canada

[11] Royal Jubilee Hosp, Victoria, BC, Canada

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2010年 / 54卷 / 03期

关键词：

FIELD GEL-ELECTROPHORESIS; CALGARY HEALTH REGION; UNITED-STATES; CLONAL GROUPS; ENTEROBACTERIACEAE; EMERGENCE; STRAINS; SPREAD; COMMUNITY; AAC(6')-IB-CR;

D O I：

10.1128/AAC.01338-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Phenotypic and genotypic methods were used to characterize extended-spectrum-beta-lactamase (ESBL)-producing Escherichia coli isolated in 2007 from 11 different Canadian medical centers. Of the 209 ESBL-producing E. coli isolates tested, 148 (71%) produced CTX-M-15, 17 (8%) produced CTX-M-14, 5 (2%) produced CTX-M-3, and 1 produced CTX-M-27. Overall, 96 (46%) of the ESBL producers belonged to clonal complex ST131, with the highest prevalence in Brampton, Calgary, and Winnipeg. ST131 is an important cause of community onset urinary tract infections due to ESBL-producing E. coli across Canada.

引用

页码：1327 / 1330

页数：4

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