Diagnostic Capacity for Invasive Fungal Infections in the Greek Paediatric Haematology-Oncology Units: Report from the Infection Working Group of the Hellenic Society of Paediatric Haematology-Oncology

被引:5
作者
Markantonatou, Anthi-Marina [1 ]
Tragiannidis, Athanasios [2 ]
Galani, Vasiliki [3 ]
Doganis, Dimitrios [4 ]
Antoniadi, Kondilia [5 ]
Tsipou, Haroula [6 ]
Lambrou, Maria [7 ]
Katzilakis, Nikolaos [8 ]
Paisiou, Anna [9 ]
Palabougiouki, Maria [2 ]
Servitzoglou, Marina [4 ]
Papakonstantinou, Eugenia [7 ]
Peristeri, Ioulia [9 ]
Stiakaki, Efthichia [8 ]
Kosmidis, Eleni [3 ]
Polychronopoulou, Sophia [5 ]
Kattamis, Antonios [6 ]
Vyzantiadis, Timoleon-Achilleas [1 ]
机构
[1] Aristotle Univ Thessaloniki, Med Sch, Dept Microbiol 1, Thessaloniki 54124, Greece
[2] Aristotle Univ Thessaloniki, AHEPA Hosp, Dept Paediat 2, Children & Adolescent Haematol Oncol Unit, Thessaloniki 53646, Greece
[3] Childrens Hosp MITERA, Paediat & Adolescent Oncol Clin, Athens 15123, Greece
[4] PA Kyriakou Childrens Hosp, Oncol Dept, Athens 11527, Greece
[5] Aghia Sophia Childrens Hosp, Dept Paediat Haematol Oncol, Athens 11527, Greece
[6] Natl & Kapodistrian Univ Athens, Aghia Sophia Childrens Hosp, Dept Paediat 1, Paediat Haematol Oncol Unit, Athens 11527, Greece
[7] Hippokrateion Hosp, Dept Paediat Haematol & Oncol, Thessaloniki 54642, Greece
[8] Univ Crete, Paediat Haematol Oncol Dept, Iraklion 70013, Greece
[9] Aghia Sophia Childrens Hosp, Stem Cell Transplant Unit, Athens 11527, Greece
关键词
invasive fungal infections; audit; diagnostic capacity; paediatric haematolgy-oncology; mycology laboratory; medical mycology; MEDICAL-MYCOLOGY; BRITISH-SOCIETY; DISEASES; GUIDELINES; MALIGNANCIES; MANAGEMENT; CANCER; BURDEN;
D O I
10.3390/jof7050357
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
An audit based on a specific questionnaire was attempted, in order to investigate the mycology laboratory diagnostic capacity for invasive fungal diseases (IFDs) in Greek Paediatric Haematology-Oncology departments/units. The study provided the relevant information for the years 2019 and 2020 and included data from all units, concerning culture-based methods and direct microscopy, phenotypic and molecular identification, sensitivity testing, serology and molecular diagnosis, as well as therapeutic drug monitoring. The target was mostly to reveal the level of laboratory coverage for hospitalised paediatric patients, independently of the possibility of performing the tests in the host hospital, or otherwise to refer the specimens elsewhere. In total, the current study demonstrated that the most important facilities and services regarding the IFD diagnostics for paediatric haematology-oncology patients in Greece are available and relatively easily accessible, with a reasonable turnaround time. Acting as an initial registry for further improvements, the audit can serve as a valuable approach to the actual situation and future perspectives. A national clinical mycology network under the auspices of the relevant scientific societies will probably facilitate collaboration between all the departments (clinical and laboratory) involved in invasive fungal infections and provide an easier approach to any necessary test for any hospitalised patient.
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页数:11
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