In situ azide formation and "click" reaction of nile red with DNA as an alternative postsynthetic route

被引：31

作者：

Beyer, Christoph ^{[1
]}

Wagenknecht, Hans-Achim ^{[1
]}

机构：

[1] Univ Regensburg, Inst Organ Chem, D-93040 Regensburg, Germany

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 13期

关键词：

CYCLOADDITION REACTION; CHEMISTRY; NUCLEOTIDE;

D O I：

10.1039/b924471a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Oligonucleotides that contain a 5-iodo-2'-deoxyuridine in the sequence can be applied for a postsynthetic "click"-type modification with ethynyl-modified nile red as a fluorescent label by in situ formation of the intermediate azide.

引用

页码：2230 / 2231

页数：2

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