In situ azide formation and "click" reaction of nile red with DNA as an alternative postsynthetic route

被引：31
作者：
Beyer, Christoph [1 ]
Wagenknecht, Hans-Achim [1 ]
机构：
[1] Univ Regensburg, Inst Organ Chem, D-93040 Regensburg, Germany
来源：
CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 13期
关键词：
CYCLOADDITION REACTION; CHEMISTRY; NUCLEOTIDE;
D O I：
10.1039/b924471a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Oligonucleotides that contain a 5-iodo-2'-deoxyuridine in the sequence can be applied for a postsynthetic "click"-type modification with ethynyl-modified nile red as a fluorescent label by in situ formation of the intermediate azide.
引用
收藏
页码：2230 / 2231
页数：2
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