共 25 条
[21]
Novel Hits in the Correction of ΔF508-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein: Synthesis, Pharmacological, and ADME Evaluation of Tetrahydropyrido[4,3-d]pyrimidines for the Potential Treatment of Cystic Fibrosis
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Pesci, Elisabetta
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Bettinetti, Laura
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Fanti, Paola
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Galietta, Luis J. V.
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La Rosa, Salvatore
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Magnoni, Letizia
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Pedemonte, Nicoletta
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Sardone, Gian Luca
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Maccari, Laura
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JOURNAL OF MEDICINAL CHEMISTRY,
2015, 58 (24)
:9697-9711

Pesci, Elisabetta
论文数: 0 引用数: 0
h-index: 0
机构:
Siena Biotech SPa, I-53100 Siena, Italy Siena Biotech SPa, I-53100 Siena, Italy

Bettinetti, Laura
论文数: 0 引用数: 0
h-index: 0
机构:
Siena Biotech SPa, I-53100 Siena, Italy Siena Biotech SPa, I-53100 Siena, Italy

Fanti, Paola
论文数: 0 引用数: 0
h-index: 0
机构:
Siena Biotech SPa, I-53100 Siena, Italy Siena Biotech SPa, I-53100 Siena, Italy

Galietta, Luis J. V.
论文数: 0 引用数: 0
h-index: 0
机构:
Ist Giovannina Gaslini, I-16148 Genoa, Italy Siena Biotech SPa, I-53100 Siena, Italy

La Rosa, Salvatore
论文数: 0 引用数: 0
h-index: 0
机构:
Siena Biotech SPa, I-53100 Siena, Italy Siena Biotech SPa, I-53100 Siena, Italy

Magnoni, Letizia
论文数: 0 引用数: 0
h-index: 0
机构:
Siena Biotech SPa, I-53100 Siena, Italy Siena Biotech SPa, I-53100 Siena, Italy

Pedemonte, Nicoletta
论文数: 0 引用数: 0
h-index: 0
机构:
Ist Giovannina Gaslini, I-16148 Genoa, Italy Siena Biotech SPa, I-53100 Siena, Italy

Sardone, Gian Luca
论文数: 0 引用数: 0
h-index: 0
机构:
Siena Biotech SPa, I-53100 Siena, Italy Siena Biotech SPa, I-53100 Siena, Italy

Maccari, Laura
论文数: 0 引用数: 0
h-index: 0
机构:
Siena Biotech SPa, I-53100 Siena, Italy Siena Biotech SPa, I-53100 Siena, Italy
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Oral resiquimod in chronic HCV infection: Safety and efficacy in 2 placebo-controlled, double-blind phase IIa studies
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Pockros, Paul J.
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Guyader, Dominque
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Patton, Heather
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Tong, Myron J.
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Wright, Terry
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McHutchison, John G.
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Meng, Tze-Chiang
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JOURNAL OF HEPATOLOGY,
2007, 47 (02)
:174-182

Pockros, Paul J.
论文数: 0 引用数: 0
h-index: 0
机构:
Scripps Clin, Div Gastroenterol Hepatol, La Jolla, CA 92037 USA Scripps Clin, Div Gastroenterol Hepatol, La Jolla, CA 92037 USA

Guyader, Dominque
论文数: 0 引用数: 0
h-index: 0
机构: Scripps Clin, Div Gastroenterol Hepatol, La Jolla, CA 92037 USA

Patton, Heather
论文数: 0 引用数: 0
h-index: 0
机构: Scripps Clin, Div Gastroenterol Hepatol, La Jolla, CA 92037 USA

Tong, Myron J.
论文数: 0 引用数: 0
h-index: 0
机构: Scripps Clin, Div Gastroenterol Hepatol, La Jolla, CA 92037 USA

Wright, Terry
论文数: 0 引用数: 0
h-index: 0
机构: Scripps Clin, Div Gastroenterol Hepatol, La Jolla, CA 92037 USA

McHutchison, John G.
论文数: 0 引用数: 0
h-index: 0
机构: Scripps Clin, Div Gastroenterol Hepatol, La Jolla, CA 92037 USA

Meng, Tze-Chiang
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h-index: 0
机构: Scripps Clin, Div Gastroenterol Hepatol, La Jolla, CA 92037 USA
[23]
Discovery of tetrahydropyridopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia
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Raheem, Izzat T.
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Breslin, Michael J.
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Fandozzi, Christine
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Fuerst, Joy
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Hill, Nicole
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Huszar, Sarah
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Kandebo, Monika
;
Kim, Somang H.
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Ma, Bennett
;
McGaughey, Georgia
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Renger, John J.
;
Schreier, John D.
;
Sharma, Sujata
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Smith, Sean
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Uslaner, Jason
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Yan, Youwei
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Coleman, Paul J.
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Cox, Christopher D.
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BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,
2012, 22 (18)
:5903-5908

Raheem, Izzat T.
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Discovery Chem, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Breslin, Michael J.
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Discovery Chem, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Fandozzi, Christine
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Pharmacokinet Pharmacodynam & Drug Metab, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Fuerst, Joy
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Basic Pharmaceut Sci, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Hill, Nicole
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Basic Pharmaceut Sci, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Huszar, Sarah
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Vivo Pharmacol, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Kandebo, Monika
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Neurosymptomat, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Kim, Somang H.
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Pharmacokinet Pharmacodynam & Drug Metab, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Ma, Bennett
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Pharmacokinet Pharmacodynam & Drug Metab, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

McGaughey, Georgia
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h-index: 0
机构:
Merck Res Labs, Chem Modeling & Informat, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Renger, John J.
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Neurosymptomat, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Schreier, John D.
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Discovery Chem, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Sharma, Sujata
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Struct Chem, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Smith, Sean
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Neurosymptomat, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Uslaner, Jason
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Vivo Pharmacol, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Yan, Youwei
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Struct Chem, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Coleman, Paul J.
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Discovery Chem, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA

Cox, Christopher D.
论文数: 0 引用数: 0
h-index: 0
机构:
Merck Res Labs, Discovery Chem, West Point, PA 19486 USA Merck Res Labs, Discovery Chem, West Point, PA 19486 USA
[24]
Identification and Optimization of Pteridinone Toll-like Receptor 7 (TLR7) Agonists for the Oral Treatment of Viral Hepatitis
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Roethle, Paul A.
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McFadden, Ryan M.
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Yang, Hong
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Hrvatin, Paul
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Hui, Hon
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Graupe, Michael
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Gallagher, Brian
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Chao, Jessica
;
Hesselgesser, Joseph
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Duatschek, Paul
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Zheng, Jim
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Lu, Bing
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Tumas, Daniel B.
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Perry, Jason
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Halcomb, Randall L.
.
JOURNAL OF MEDICINAL CHEMISTRY,
2013, 56 (18)
:7324-7333

Roethle, Paul A.
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

McFadden, Ryan M.
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

Yang, Hong
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

Hrvatin, Paul
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

Hui, Hon
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

Graupe, Michael
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

Gallagher, Brian
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

Chao, Jessica
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

Hesselgesser, Joseph
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Clin Virol, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

Duatschek, Paul
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Clin Virol, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

Zheng, Jim
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Drug Metab, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

Lu, Bing
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Drug Metab, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

Tumas, Daniel B.
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Biol, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

Perry, Jason
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Struct Chem, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA

Halcomb, Randall L.
论文数: 0 引用数: 0
h-index: 0
机构:
Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA Gilead Sci Inc, Dept Med Chem, Foster City, CA 94404 USA
[25]
The Third Signal Cytokine IL-12 Rescues the Anti-Viral Function of Exhausted HBV-Specific CD8 T Cells
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Schurich, Anna
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Pallett, Laura J.
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Lubowiecki, Marcin
;
Singh, Harsimran D.
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Gill, Upkar S.
;
Kennedy, Patrick T.
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Nastouli, Eleni
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Tanwar, Sudeep
;
Rosenberg, William
;
Maini, Mala K.
.
PLOS PATHOGENS,
2013, 9 (03)

Schurich, Anna
论文数: 0 引用数: 0
h-index: 0
机构:
UCL, Div Infect & Immun, London, England UCL, Div Infect & Immun, London, England

Pallett, Laura J.
论文数: 0 引用数: 0
h-index: 0
机构:
UCL, Div Infect & Immun, London, England UCL, Div Infect & Immun, London, England

Lubowiecki, Marcin
论文数: 0 引用数: 0
h-index: 0
机构:
UCL, Div Infect & Immun, London, England UCL, Div Infect & Immun, London, England

Singh, Harsimran D.
论文数: 0 引用数: 0
h-index: 0
机构:
UCL, Div Infect & Immun, London, England
UCL, Ctr Hepatol, London, England UCL, Div Infect & Immun, London, England

Gill, Upkar S.
论文数: 0 引用数: 0
h-index: 0
机构:
Barts & London Queen Marys Sch Med & Dent, Ctr Digest Dis, London, England UCL, Div Infect & Immun, London, England

Kennedy, Patrick T.
论文数: 0 引用数: 0
h-index: 0
机构:
Barts & London Queen Marys Sch Med & Dent, Ctr Digest Dis, London, England UCL, Div Infect & Immun, London, England

Nastouli, Eleni
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Coll London Hosp, Dept Clin Microbiol & Virol, London, England UCL, Div Infect & Immun, London, England

Tanwar, Sudeep
论文数: 0 引用数: 0
h-index: 0
机构:
UCL, Ctr Hepatol, London, England UCL, Div Infect & Immun, London, England

Rosenberg, William
论文数: 0 引用数: 0
h-index: 0
机构:
UCL, Ctr Hepatol, London, England UCL, Div Infect & Immun, London, England

Maini, Mala K.
论文数: 0 引用数: 0
h-index: 0
机构:
UCL, Div Infect & Immun, London, England UCL, Div Infect & Immun, London, England