Parsiguine, a novel antimicrobial substance from Fischerella ambigua

被引：58

作者：

Ghasemi, Y

Yazdi, MT

Shafiee, A

Amini, M

Shokravi, S

Zarrini, G

机构：

[1] Univ Tehran Med Sci, Fac Pharm, Dept Pharmaceut Biotechnol, Tehran 14174, Iran

[2] Univ Tehran Med Sci, Fac Pharm, Dept Med Chem, Tehran 14174, Iran

[3] Shaheed Beheshti Univ, Appl Sci Ctr, Dept Biol, Tehran, Iran

来源：

PHARMACEUTICAL BIOLOGY | 2004年 / 42卷 / 4-5期

关键词：

antibiotic; antimicrobial substance; blue-green algae; cyanobacteria; Fischerella ambigua;

D O I：

10.1080/13880200490511918

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Fischerella ambigua was isolated during a screening program from soil sample collected from paddy-fields in the north of Iran. It was shown that it excreted broad-spectrum antibacterial and antifungal substance in culture medium. Bioassay-guided fraction of the culture medium of the F ambigua led to isolation of a novel antimicrobial substance, which was named parsiguine, that exhibited antifungal and antibacterial activities. The structure of parsiguine was determined by spectroscopic methods, including NMR, MS, IR, and UV.

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收藏

页码：318 / 322

页数：5

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