Old and new pathogenic Nakaseomyces species: epidemiology, biology, identification, pathogenicity and antifungal resistance

被引:45
作者
Angoulvant, A. [1 ,2 ]
Guitard, J. [3 ,4 ]
Hennequin, C. [3 ,4 ]
机构
[1] Univ Hosp Bicetre, AP HP, Lab Parasitol Mycol, F-94275 Le Kremlin Bicetre, France
[2] Univ Paris 11, Genet Quantitat & Evolut, CNRS, UMR 8621, F-91190 Gif Sur Yvette, France
[3] Univ Hosp St Antoine, AP HP, Serv Parasitol Mycol, F-75012 Paris, France
[4] Univ Paris 06, Sorbonne Univ, Ctr Immunol & Malad Infect CIMI Paris, CR7, F-75013 Paris, France
关键词
C; glabrata; nivariensis; C. bracarensis: epidemiology; biology; pathogenicity; ESCMID-ASTERISK GUIDELINE; CANDIDA-GLABRATA FUNGEMIA; VULVO-VAGINAL CANDIDIASIS; CATHETER-RELATED FUNGEMIA; CRITICALLY-ILL PATIENTS; INTENSIVE-CARE-UNIT; BLOOD-STREAM; INVASIVE CANDIDIASIS; RAPID IDENTIFICATION; ORAL CANDIDA;
D O I
10.1093/femsyr/fov114
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
During the previous decades, as the number of immunocompromised patients, the average age of Western populations and the widespread use of indwelling medical devices have increased concomitantly, so has the incidence of infections caused by Candida species. Candida albicans remains the most frequently isolated agent of candidiasis. However, C. glabrata now accounts for a substantial part of clinical isolates, ranking number two among the etiologic agents of either superficial or invasive candidiasis in North America and Europe. Along with C. glabrata and belonging to the Nakaseomyces clade, two new species, C. nivariensis and C bracarensis have recently been described as emerging pathogens. This review provides information on the current state of knowledge on the epidemiology, biology, identification, pathogenicity and antifungal resistance of C. glabrata, C. nivariensis and C. bracarensis.
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页数:13
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