Subthalamic Nucleus Stimulation Affects Fear and Sadness Recognition in Parkinson's Disease

被引:55
|
作者
Peron, Julie [1 ,2 ]
Biseul, Isabelle [1 ,2 ]
Leray, Emmanuelle [2 ,3 ]
Vicente, Siobhan [1 ,2 ,4 ]
Le Jeune, Florence [2 ,5 ]
Drapier, Sophie [1 ,2 ]
Drapier, Dominique [2 ,4 ]
Sauleau, Paul [1 ,2 ]
Haegelen, Claire [2 ,6 ]
Verin, Marc [1 ,2 ]
机构
[1] CHU Rennes, Hop Pontchaillou, Neurol Clin, F-35033 Rennes, France
[2] Univ Rennes 1, CHU Rennes, Hop Pontchaillou, Unite Rech Univ Comportement & Noyaux Gris Centra, F-35014 Rennes, France
[3] CHU Rennes, Hop Pontchaillou, Serv Epidemiol & Sante Publ, F-35033 Rennes, France
[4] Ctr Hosp Guillaume Regnier, SHU Psychiat Adulte, Rennes, France
[5] Ctr Eugene Marquis, Nucl Med Serv, Rennes, France
[6] CHU Rennes, Hop Pontchaillou, Serv Neurochirurg, F-35033 Rennes, France
关键词
subthalamic nucleus; deep brain stimulation; Parkinson's disease; emotion recognition; limbic system; DEEP BRAIN-STIMULATION; FACIAL EMOTION; EXPRESSIONS; CORTEX; MOTOR; ACTIVATION;
D O I
10.1037/a0017433
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) in Parkinson's disease (PD) can produce emotional disorders that have been linked to disturbance of the STN's limbic territory. The aim of this study was to confirm the impairment of the recognition of facial emotions (RFE) induced by STN DBS, not only ruling out the effect of the disease's natural progression in relation to the effect of DBS, but also assessing the influence of modifications in dopamine replacement therapy (DRT) following STN DBS. RFE was investigated in 24 PD patients who underwent STN DBS and 20 PD patients treated with apomorphine. They were assessed 3 months before and after treatment. The 2 patient groups were compared with a group of 30 healthy matched controls. The results showed that RFE for negative emotions (fear and sadness) was impaired in only the STN DBS group in the posttreatment condition and was unrelated to DRT. Results confirm the selective reduction of RFE induced by STN DBS, due neither to the disease's natural progression nor to modifications in DRT.
引用
收藏
页码:1 / 8
页数:8
相关论文
共 50 条
  • [21] Language recovery following subthalamic nucleus stimulation in Parkinson's disease
    Zanini, S
    Melatini, A
    Capus, L
    Gioulis, M
    Vassallo, A
    Bava, A
    NEUROREPORT, 2003, 14 (03) : 511 - 516
  • [22] Impact of subthalamic nucleus stimulation on the initiation of gait in Parkinson's disease
    Crenna, P.
    Carpinella, I.
    Rabuffetti, M.
    Rizzone, M.
    Lopiano, L.
    Lanotte, M.
    Ferrarin, M.
    EXPERIMENTAL BRAIN RESEARCH, 2006, 172 (04) : 519 - 532
  • [23] Mortality in patients with Parkinson's disease treated by stimulation of the subthalamic nucleus
    Schuepbach, Michael W. M.
    Welter, Marie Laure
    Bonnet, Anne Marie
    Elbaz, Alexis
    Grossardt, Brandon R.
    Mesnage, Valerie
    Houeto, Jean Luc
    Maltête, David
    Mallet, Luc
    Rocca, Walter A.
    Mallet, Alain
    Agid, Yves
    MOVEMENT DISORDERS, 2007, 22 (02) : 257 - 261
  • [24] Deep brain stimulation of the subthalamic nucleus in patient with Parkinson's disease
    Fukaya, C
    NEUROLOGICAL SURGERY, 2004, 32 (08): : 887 - 893
  • [25] Does subthalamic nucleus stimulation induce apathy in Parkinson's disease?
    Drapier, D.
    Drapier, S.
    Sauleau, P.
    Haegelen, C.
    Raoul, S.
    Biseul, I.
    Peron, J.
    Lallement, F.
    Rivier, I.
    Reymann, J. M.
    Edan, G.
    Verin, M.
    Millet, B.
    JOURNAL OF NEUROLOGY, 2006, 253 (08) : 1083 - 1091
  • [26] Suicide Attempts after Subthalamic Nucleus Stimulation for Parkinson's Disease
    Rodrigues, Ana M.
    Rosas, Maria J.
    Gago, Miguel F.
    Sousa, Claudia
    Fonseca, Rosalia
    Linhares, Paulo
    Basto, Margarida A.
    Sousa, Graca
    Garrett, Carolina
    Vaz, Rui
    EUROPEAN NEUROLOGY, 2010, 63 (03) : 176 - 179
  • [27] Impact of subthalamic nucleus stimulation on the initiation of gait in Parkinson’s disease
    P. Crenna
    I. Carpinella
    M. Rabuffetti
    M. Rizzone
    L. Lopiano
    M. Lanotte
    M. Ferrarin
    Experimental Brain Research, 2006, 172 : 519 - 532
  • [28] Efficacy of bilateral subthalamic nucleus (STN) stimulation in Parkinson's disease
    Erola, T
    Heikkinen, ER
    Haapaniemi, T
    Tuominen, J
    Juolasmaa, A
    Myllylä, VV
    ACTA NEUROCHIRURGICA, 2006, 148 (04) : 389 - 394
  • [29] Subthalamic nucleus stimulation influences expression and suppression of impulsive behaviour in Parkinson's disease
    Wylie, Scott A.
    Ridderinkhof, K. Richard
    Elias, William J.
    Frysinger, Robert C.
    Bashore, Theodore R.
    Downs, Kara E.
    van Wouwe, Nelleke C.
    van den Wildenberg, Wery P. M.
    BRAIN, 2010, 133 : 3611 - 3624
  • [30] Subthalamic Nucleus Stimulation Affects Theory of Mind Network: A PET Study in Parkinson's Disease
    Peron, Julie
    Le Jeune, Florence
    Haegelen, Claire
    Dondaine, Thibaut
    Drapier, Dominique
    Sauleau, Paul
    Reymann, Jean-Michel
    Drapier, Sophie
    Rouaud, Tiphaine
    Millet, Bruno
    Verin, Marc
    PLOS ONE, 2010, 5 (03):