Improving the translational potential of rodent models to study the behavioral and pathophysiological effects of repetitive mild traumatic brain injury

被引：2
|
作者：
Huibregtse, Megan E. [1 ]
机构：
[1] Indiana Univ, Sch Publ Hlth, Dept Kinesiol, Bloomington, IN USA
来源：
JOURNAL OF NEUROPHYSIOLOGY | 2018年 / 120卷 / 01期
关键词：
concussions; electrophysiology; repetitive mild traumatic brain injury; rodent model; HEAD-INJURY; ENCEPHALOPATHY; CONCUSSION; CORTEX;
D O I：
10.1152/jn.00898.2017
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Chronic traumatic encephalopathy (CTE) is thought to be caused by repetitive head impacts. Consequently, there is a need to develop rodent models to better understand the behavioral and pathophysiological changes of repetitive mild traumatic brain injury (rmTBI) and to determine the link between rmTBI and CTE. This Neuro Forum article reviews recent rodent rmTBI models, comparing the impact methods and outcome measures in terms of translational potential.
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页码：1 / 3
页数：3
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